NFIA


NFIA
Nuclear factor I/A
Identifiers
Symbols NFIA; DKFZp434L0422; DKFZp686J23256; FLJ39164; KIAA1439; NFI-L
External IDs OMIM600727 MGI108056 HomoloGene4086 GeneCards: NFIA Gene
Orthologs
Species Human Mouse
Entrez 4774 18027
Ensembl ENSG00000162599 ENSMUSG00000028565
UniProt Q12857 Q3UTK6
RefSeq (mRNA) NM_001134673.3 NM_010905
RefSeq (protein) NP_001128145.1 NP_035035
Location (UCSC) Chr 1:
61.33 – 61.93 Mb
Chr 4:
97.44 – 97.87 Mb
PubMed search [1] [2]

Nuclear factor 1 A-type is a protein that in humans is encoded by the NFIA gene.[1][2]

Nuclear factor I (NFI) proteins constitute a family of dimeric DNA-binding proteins with similar, and possibly identical, DNA-binding specificity. They function as cellular transcription factors and as replication factors for adenovirus DNA replication. Diversity in this protein family is generated by multiple genes, differential splicing, and heterodimerization.[supplied by OMIM][2]

References

  1. ^ Qian F, Kruse U, Lichter P, Sippel AE (Dec 1995). "Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH". Genomics 28 (1): 66–73. doi:10.1006/geno.1995.1107. PMID 7590749. 
  2. ^ a b "Entrez Gene: NFIA nuclear factor I/A". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4774. 

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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