SOX5


SOX5

SRY (sex determining region Y)-box 5, also known as SOX5, is a human gene.cite web | title = Entrez Gene: SOX5 SRY (sex determining region Y)-box 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6660| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene.cite web | title = Entrez Gene: SOX5 SRY (sex determining region Y)-box 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6660| accessdate = ]

ee also

* SOX genes

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kamachi Y, Uchikawa M, Kondoh H |title=Pairing SOX off: with partners in the regulation of embryonic development. |journal=Trends Genet. |volume=16 |issue= 4 |pages= 182–7 |year= 2000 |pmid= 10729834 |doi=
*cite journal | author=Bowles J, Schepers G, Koopman P |title=Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators. |journal=Dev. Biol. |volume=227 |issue= 2 |pages= 239–55 |year= 2001 |pmid= 11071752 |doi= 10.1006/dbio.2000.9883
*cite journal | author=Wilson M, Koopman P |title=Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators. |journal=Curr. Opin. Genet. Dev. |volume=12 |issue= 4 |pages= 441–6 |year= 2003 |pmid= 12100890 |doi=
*cite journal | author=Schepers GE, Teasdale RD, Koopman P |title=Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families. |journal=Dev. Cell |volume=3 |issue= 2 |pages= 167–70 |year= 2002 |pmid= 12194848 |doi=
*cite journal | author=Denny P, Swift S, Brand N, "et al." |title=A conserved family of genes related to the testis determining gene, SRY. |journal=Nucleic Acids Res. |volume=20 |issue= 11 |pages= 2887 |year= 1992 |pmid= 1614875 |doi=
*cite journal | author=Connor F, Cary PD, Read CM, "et al." |title=DNA binding and bending properties of the post-meiotically expressed Sry-related protein Sox-5. |journal=Nucleic Acids Res. |volume=22 |issue= 16 |pages= 3339–46 |year= 1994 |pmid= 8078769 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Wunderle VM, Critcher R, Ashworth A, Goodfellow PN |title=Cloning and characterization of SOX5, a new member of the human SOX gene family. |journal=Genomics |volume=36 |issue= 2 |pages= 354–8 |year= 1997 |pmid= 8812465 |doi= 10.1006/geno.1996.0474
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Lefebvre V, Li P, de Crombrugghe B |title=A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene. |journal=EMBO J. |volume=17 |issue= 19 |pages= 5718–33 |year= 1998 |pmid= 9755172 |doi= 10.1093/emboj/17.19.5718
*cite journal | author=Uusitalo H, Hiltunen A, Ahonen M, "et al." |title=Accelerated up-regulation of L-Sox5, Sox6, and Sox9 by BMP-2 gene transfer during murine fracture healing. |journal=J. Bone Miner. Res. |volume=16 |issue= 10 |pages= 1837–45 |year= 2002 |pmid= 11585348 |doi=
*cite journal | author=Zafarana G, Gillis AJ, van Gurp RJ, "et al." |title=Coamplification of DAD-R, SOX5, and EKI1 in human testicular seminomas, with specific overexpression of DAD-R, correlates with reduced levels of apoptosis and earlier clinical manifestation. |journal=Cancer Res. |volume=62 |issue= 6 |pages= 1822–31 |year= 2002 |pmid= 11912161 |doi=
*cite journal | author=Ikeda T, Zhang J, Chano T, "et al." |title=Identification and characterization of the human long form of Sox5 (L-SOX5) gene. |journal=Gene |volume=298 |issue= 1 |pages= 59–68 |year= 2003 |pmid= 12406576 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285

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