MAFB (gene)

MAFB (gene)

V-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian), also known as MAFB, is a human gene.cite web | title = Entrez Gene: MAFB v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)| url =| accessdate = ]

section_title =
summary_text = The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene contains no introns.cite web | title = Entrez Gene: MAFB v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)| url =| accessdate = ]


Further reading

citations =
*cite journal | author=Cordes SP, Barsh GS |title=The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor. |journal=Cell |volume=79 |issue= 6 |pages= 1025–34 |year= 1995 |pmid= 8001130 |doi=
*cite journal | author=Sieweke MH, Tekotte H, Frampton J, Graf T |title=MafB is an interaction partner and repressor of Ets-1 that inhibits erythroid differentiation. |journal=Cell |volume=85 |issue= 1 |pages= 49–60 |year= 1996 |pmid= 8620536 |doi=
*cite journal | author=Stoffel M, Le Beau MM, Espinosa R, "et al." |title=A yeast artificial chromosome-based map of the region of chromosome 20 containing the diabetes-susceptibility gene, MODY1, and a myeloid leukemia related gene. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 9 |pages= 3937–41 |year= 1996 |pmid= 8632993 |doi=
*cite journal | author=Wang PW, Eisenbart JD, Cordes SP, "et al." |title=Human KRML (MAFB): cDNA cloning, genomic structure, and evaluation as a candidate tumor suppressor gene in myeloid leukemias. |journal=Genomics |volume=59 |issue= 3 |pages= 275–81 |year= 1999 |pmid= 10444328 |doi= 10.1006/geno.1999.5884
*cite journal | author=Li R, Pei H, Watson DK, Papas TS |title=EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes. |journal=Oncogene |volume=19 |issue= 6 |pages= 745–53 |year= 2000 |pmid= 10698492 |doi= 10.1038/sj.onc.1203385
*cite journal | author=Yamada K, Tomita H, Yoshiura K, "et al." |title=An autosomal dominant posterior polar cataract locus maps to human chromosome 20p12-q12. |journal=Eur. J. Hum. Genet. |volume=8 |issue= 7 |pages= 535–9 |year= 2000 |pmid= 10909854 |doi= 10.1038/sj.ejhg.5200485
*cite journal | author=Deloukas P, Matthews LH, Ashurst J, "et al." |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Rosenberger G, Jantke I, Gal A, Kutsche K |title=Interaction of alphaPIX (ARHGEF6) with beta-parvin (PARVB) suggests an involvement of alphaPIX in integrin-mediated signaling. |journal=Hum. Mol. Genet. |volume=12 |issue= 2 |pages= 155–67 |year= 2003 |pmid= 12499396 |doi=
*cite journal | author=Hashizume H, Hamalainen H, Sun Q, "et al." |title=Downregulation of mafB expression in T-helper cells during early differentiation in vitro. |journal=Scand. J. Immunol. |volume=57 |issue= 1 |pages= 28–34 |year= 2004 |pmid= 12542795 |doi=
*cite journal | author=Fernández-Calotti PX, Salamone G, Gamberale R, "et al." |title=Downregulation of mac-1 expression in monocytes by surface-bound IgG. |journal=Scand. J. Immunol. |volume=57 |issue= 1 |pages= 35–44 |year= 2004 |pmid= 12542796 |doi=
*cite journal | author=Mechta-Grigoriou F, Giudicelli F, Pujades C, "et al." |title=c-jun regulation and function in the developing hindbrain. |journal=Dev. Biol. |volume=258 |issue= 2 |pages= 419–31 |year= 2003 |pmid= 12798298 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Kim JC, Badano JL, Sibold S, "et al." |title=The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression. |journal=Nat. Genet. |volume=36 |issue= 5 |pages= 462–70 |year= 2004 |pmid= 15107855 |doi= 10.1038/ng1352
*cite journal | author=Sevinsky JR, Whalen AM, Ahn NG |title=Extracellular signal-regulated kinase induces the megakaryocyte GPIIb/CD41 gene through MafB/Kreisler. |journal=Mol. Cell. Biol. |volume=24 |issue= 10 |pages= 4534–45 |year= 2004 |pmid= 15121870 |doi=
*cite journal | author=Petersen HH, Hilpert J, Jacobsen C, "et al." |title=Low-density lipoprotein receptor-related protein interacts with MafB, a regulator of hindbrain development. |journal=FEBS Lett. |volume=565 |issue= 1-3 |pages= 23–7 |year= 2004 |pmid= 15135046 |doi= 10.1016/j.febslet.2004.03.069
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Bakri Y, Sarrazin S, Mayer UP, "et al." |title=Balance of MafB and PU.1 specifies alternative macrophage or dendritic cell fate. |journal=Blood |volume=105 |issue= 7 |pages= 2707–16 |year= 2005 |pmid= 15598817 |doi= 10.1182/blood-2004-04-1448
*cite journal | author=Gemelli C, Montanari M, Tenedini E, "et al." |title=Virally mediated MafB transduction induces the monocyte commitment of human CD34+ hematopoietic stem/progenitor cells. |journal=Cell Death Differ. |volume=13 |issue= 10 |pages= 1686–96 |year= 2006 |pmid= 16456583 |doi= 10.1038/sj.cdd.4401860
*cite journal | author=Lee LC, Zhang AY, Chong AK, "et al." |title=Expression of a novel gene, MafB, in Dupuytren's disease. |journal=The Journal of hand surgery |volume=31 |issue= 2 |pages= 211–8 |year= 2006 |pmid= 16473681 |doi= 10.1016/j.jhsa.2005.09.007

External links


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