CCAAT/enhancer binding protein (C/EBP), delta, also known as CEBPD, is a human gene.

section_title =
summary_text = The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages.cite web | title = Entrez Gene: CEBPD CCAAT/enhancer binding protein (C/EBP), delta| url =| accessdate = ]

ee also

* Ccaat-enhancer-binding proteins


Further reading

citations =
*cite journal | author=Sladek FM, Darnell JE |title=Mechanisms of liver-specific gene expression. |journal=Curr. Opin. Genet. Dev. |volume=2 |issue= 2 |pages= 256–9 |year= 1992 |pmid= 1638120 |doi=
*cite journal | author=Kinoshita S, Akira S, Kishimoto T |title=A member of the C/EBP family, NF-IL6 beta, forms a heterodimer and transcriptionally synergizes with NF-IL6. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=89 |issue= 4 |pages= 1473–6 |year= 1992 |pmid= 1741402 |doi=
*cite journal | author=Cao Z, Umek RM, McKnight SL |title=Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. |journal=Genes Dev. |volume=5 |issue= 9 |pages= 1538–52 |year= 1991 |pmid= 1840554 |doi=
*cite journal | author=Williams SC, Cantwell CA, Johnson PF |title=A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro. |journal=Genes Dev. |volume=5 |issue= 9 |pages= 1553–67 |year= 1991 |pmid= 1884998 |doi=
*cite journal | author=Nagulapalli S, Pongubala JM, Atchison ML |title=Multiple proteins physically interact with PU.1. Transcriptional synergy with NF-IL6 beta (C/EBP delta, CRP3). |journal=J. Immunol. |volume=155 |issue= 9 |pages= 4330–8 |year= 1995 |pmid= 7594592 |doi=
*cite journal | author=Wood S, Schertzer M, Yaremko ML |title=Sequence identity locates CEBPD and FGFR1 to mapped human loci within proximal 8p. |journal=Cytogenet. Cell Genet. |volume=70 |issue= 3-4 |pages= 188–91 |year= 1995 |pmid= 7789168 |doi=
*cite journal | author=Cleutjens CB, van Eekelen CC, van Dekken H, "et al." |title=The human C/EBP delta (CRP3/CELF) gene: structure and chromosomal localization. |journal=Genomics |volume=16 |issue= 2 |pages= 520–3 |year= 1993 |pmid= 8314590 |doi=
*cite journal | author=Chen PL, Riley DJ, Chen Y, Lee WH |title=Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs. |journal=Genes Dev. |volume=10 |issue= 21 |pages= 2794–804 |year= 1997 |pmid= 8946919 |doi=
*cite journal | author=Xia C, Cheshire JK, Patel H, Woo P |title=Cross-talk between transcription factors NF-kappa B and C/EBP in the transcriptional regulation of genes. |journal=Int. J. Biochem. Cell Biol. |volume=29 |issue= 12 |pages= 1525–39 |year= 1998 |pmid= 9570146 |doi=
*cite journal | author=Zhu Y, Saunders MA, Yeh H, "et al." |title=Dynamic regulation of cyclooxygenase-2 promoter activity by isoforms of CCAAT/enhancer-binding proteins. |journal=J. Biol. Chem. |volume=277 |issue= 9 |pages= 6923–8 |year= 2002 |pmid= 11741938 |doi= 10.1074/jbc.M108075200
*cite journal | author=Angeloni D, Lee JD, Johnson BE, "et al." |title=C306A single nucleotide polymorphism in the human CEBPD gene that maps at 8p11.1-p11.2. |journal=Mol. Cell. Probes |volume=15 |issue= 6 |pages= 395–7 |year= 2002 |pmid= 11851384 |doi= 10.1006/mcpr.2001.0377
*cite journal | author=Gao H, Parkin S, Johnson PF, Schwartz RC |title=C/EBP gamma has a stimulatory role on the IL-6 and IL-8 promoters. |journal=J. Biol. Chem. |volume=277 |issue= 41 |pages= 38827–37 |year= 2002 |pmid= 12177065 |doi= 10.1074/jbc.M206224200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Dearth LR, DeWille J |title=Posttranscriptional and posttranslational regulation of C/EBP delta in G0 growth-arrested mammary epithelial cells. |journal=J. Biol. Chem. |volume=278 |issue= 13 |pages= 11246–55 |year= 2003 |pmid= 12554732 |doi= 10.1074/jbc.M207930200
*cite journal | author=Milde-Langosch K, Löning T, Bamberger AM |title=Expression of the CCAAT/enhancer-binding proteins C/EBPalpha, C/EBPbeta and C/EBPdelta in breast cancer: correlations with clinicopathologic parameters and cell-cycle regulatory proteins. |journal=Breast Cancer Res. Treat. |volume=79 |issue= 2 |pages= 175–85 |year= 2003 |pmid= 12825852 |doi=
*cite journal | author=Kovács KA, Steinmann M, Magistretti PJ, "et al." |title=CCAAT/enhancer-binding protein family members recruit the coactivator CREB-binding protein and trigger its phosphorylation. |journal=J. Biol. Chem. |volume=278 |issue= 38 |pages= 36959–65 |year= 2003 |pmid= 12857754 |doi= 10.1074/jbc.M303147200
*cite journal | author=Chen YW, Hubal MJ, Hoffman EP, "et al." |title=Molecular responses of human muscle to eccentric exercise. |journal=J. Appl. Physiol. |volume=95 |issue= 6 |pages= 2485–94 |year= 2004 |pmid= 12937035 |doi= 10.1152/japplphysiol.01161.2002
*cite journal | author=Li R, Strohmeyer R, Liang Z, "et al." |title=CCAAT/enhancer binding protein delta (C/EBPdelta) expression and elevation in Alzheimer's disease. |journal=Neurobiol. Aging |volume=25 |issue= 8 |pages= 991–9 |year= 2004 |pmid= 15212823 |doi= 10.1016/j.neurobiolaging.2003.10.016
*cite journal | author=Sivko GS, Sanford DC, Dearth LD, "et al." |title=CCAAT/Enhancer binding protein delta (c/EBPdelta) regulation and expression in human mammary epithelial cells: II. Analysis of activating signal transduction pathways, transcriptional, post-transcriptional, and post-translational control. |journal=J. Cell. Biochem. |volume=93 |issue= 4 |pages= 844–56 |year= 2005 |pmid= 15389878 |doi= 10.1002/jcb.20224

External links


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  • C/EBPs — Dieser Artikel oder Abschnitt bedarf einer Überarbeitung. Näheres ist auf der Diskussionsseite angegeben. Hilf mit, ihn zu verbessern, und entferne anschließend diese Markierung …   Deutsch Wikipedia

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  • CCAAT/enhancer-binding proteins — Dieser Artikel oder Abschnitt bedarf einer Überarbeitung. Näheres ist auf der Diskussionsseite angegeben. Hilf mit, ihn zu verbessern, und entferne anschließend diese Markierung …   Deutsch Wikipedia

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