HOXC13

Homeobox C13, also known as HOXC13, is a human gene.cite web | title = Entrez Gene: HOXC13 homeobox C13| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3229| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the development of hair, nail, and filiform papilla.cite web | title = Entrez Gene: HOXC13 homeobox C13| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3229| accessdate = ]

ee also

* Homeobox

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Godwin AR, Capecchi MR |title=Hair defects in Hoxc13 mutant mice. |journal=J. Investig. Dermatol. Symp. Proc. |volume=4 |issue= 3 |pages= 244–7 |year= 2000 |pmid= 10674376 |doi=
*cite journal | author=Panagopoulos I, Isaksson M, Billström R, "et al." |title=Fusion of the NUP98 gene and the homeobox gene HOXC13 in acute myeloid leukemia with t(11;12)(p15;q13). |journal=Genes Chromosomes Cancer |volume=36 |issue= 1 |pages= 107–12 |year= 2003 |pmid= 12461755 |doi= 10.1002/gcc.10139
*cite journal | author=Scott MP |title=Vertebrate homeobox gene nomenclature. |journal=Cell |volume=71 |issue= 4 |pages= 551–3 |year= 1992 |pmid= 1358459 |doi=
*cite journal | author=McAlpine PJ, Shows TB |title=Nomenclature for human homeobox genes. |journal=Genomics |volume=7 |issue= 3 |pages= 460 |year= 1990 |pmid= 1973146 |doi=
*cite journal | author=Acampora D, D'Esposito M, Faiella A, "et al." |title=The human HOX gene family. |journal=Nucleic Acids Res. |volume=17 |issue= 24 |pages= 10385–402 |year= 1990 |pmid= 2574852 |doi=
*cite journal | author=Rabin M, Ferguson-Smith A, Hart CP, Ruddle FH |title=Cognate homeo-box loci mapped on homologous human and mouse chromosomes. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=83 |issue= 23 |pages= 9104–8 |year= 1987 |pmid= 2878432 |doi=
*cite journal | author=Apiou F, Flagiello D, Cillo C, "et al." |title=Fine mapping of human HOX gene clusters. |journal=Cytogenet. Cell Genet. |volume=73 |issue= 1-2 |pages= 114–5 |year= 1996 |pmid= 8646877 |doi=
*cite journal | author=Flagiello D, Gibaud A, Dutrillaux B, "et al." |title=Distinct patterns of all-trans retinoic acid dependent expression of HOXB and HOXC homeogenes in human embryonal and small-cell lung carcinoma cell lines. |journal=FEBS Lett. |volume=415 |issue= 3 |pages= 263–7 |year= 1997 |pmid= 9357979 |doi=
*cite journal | author=de Stanchina E, Gabellini D, Norio P, "et al." |title=Selection of homeotic proteins for binding to a human DNA replication origin. |journal=J. Mol. Biol. |volume=299 |issue= 3 |pages= 667–80 |year= 2000 |pmid= 10835276 |doi= 10.1006/jmbi.2000.3782
*cite journal | author=Kulessa H, Turk G, Hogan BL |title=Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle. |journal=EMBO J. |volume=19 |issue= 24 |pages= 6664–74 |year= 2001 |pmid= 11118201 |doi= 10.1093/emboj/19.24.6664
*cite journal | author=Kosaki K, Kosaki R, Suzuki T, "et al." |title=Complete mutation analysis panel of the 39 human HOX genes. |journal=Teratology |volume=65 |issue= 2 |pages= 50–62 |year= 2002 |pmid= 11857506 |doi= 10.1002/tera.10009
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Pruett ND, Tkatchenko TV, Jave-Suarez L, "et al." |title=Krtap16, characterization of a new hair keratin-associated protein (KAP) gene complex on mouse chromosome 16 and evidence for regulation by Hoxc13. |journal=J. Biol. Chem. |volume=279 |issue= 49 |pages= 51524–33 |year= 2005 |pmid= 15385554 |doi= 10.1074/jbc.M404331200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

External links

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