HOXB9


HOXB9

Homeobox B9, also known as HOXB9, is a human gene.cite web | title = Entrez Gene: HOXB9 homeobox B9| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3219| accessdate = ]

PBB_Summary
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summary_text = This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer.cite web | title = Entrez Gene: HOXB9 homeobox B9| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3219| accessdate = ]

ee also

* Homeobox

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Scott MP |title=Vertebrate homeobox gene nomenclature. |journal=Cell |volume=71 |issue= 4 |pages= 551–3 |year= 1992 |pmid= 1358459 |doi=
*cite journal | author=Deguchi Y, Kehrl JH |title=Selective expression of two homeobox genes in CD34-positive cells from human bone marrow. |journal=Blood |volume=78 |issue= 2 |pages= 323–8 |year= 1991 |pmid= 1712647 |doi=
*cite journal | author=McAlpine PJ, Shows TB |title=Nomenclature for human homeobox genes. |journal=Genomics |volume=7 |issue= 3 |pages= 460 |year= 1990 |pmid= 1973146 |doi=
*cite journal | author=Peverali FA, D'Esposito M, Acampora D, "et al." |title=Expression of HOX homeogenes in human neuroblastoma cell culture lines. |journal=Differentiation |volume=45 |issue= 1 |pages= 61–9 |year= 1991 |pmid= 1981366 |doi=
*cite journal | author=Giampaolo A, Acampora D, Zappavigna V, "et al." |title=Differential expression of human HOX-2 genes along the anterior-posterior axis in embryonic central nervous system. |journal=Differentiation |volume=40 |issue= 3 |pages= 191–7 |year= 1989 |pmid= 2570724 |doi=
*cite journal | author=Acampora D, D'Esposito M, Faiella A, "et al." |title=The human HOX gene family. |journal=Nucleic Acids Res. |volume=17 |issue= 24 |pages= 10385–402 |year= 1990 |pmid= 2574852 |doi=
*cite journal | author=Boncinelli E, Acampora D, Pannese M, "et al." |title=Organization of human class I homeobox genes. |journal=Genome |volume=31 |issue= 2 |pages= 745–56 |year= 1990 |pmid= 2576652 |doi=
*cite journal | author=Apiou F, Flagiello D, Cillo C, "et al." |title=Fine mapping of human HOX gene clusters. |journal=Cytogenet. Cell Genet. |volume=73 |issue= 1-2 |pages= 114–5 |year= 1996 |pmid= 8646877 |doi=
*cite journal | author=Ohnishi K, Tobita T, Sinjo K, "et al." |title=Modulation of homeobox B6 and B9 genes expression in human leukemia cell lines during myelomonocytic differentiation. |journal=Leuk. Lymphoma |volume=31 |issue= 5-6 |pages= 599–608 |year= 1999 |pmid= 9922051 |doi=
*cite journal | author=Prévôt D, Voeltzel T, Birot AM, "et al." |title=The leukemia-associated protein Btg1 and the p53-regulated protein Btg2 interact with the homeoprotein Hoxb9 and enhance its transcriptional activation. |journal=J. Biol. Chem. |volume=275 |issue= 1 |pages= 147–53 |year= 2000 |pmid= 10617598 |doi=
*cite journal | author=Calvo R, West J, Franklin W, "et al." |title=Altered HOX and WNT7A expression in human lung cancer. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 23 |pages= 12776–81 |year= 2001 |pmid= 11070089 |doi= 10.1073/pnas.97.23.12776
*cite journal | author=de Pinieux G, Legrier ME, Poirson-Bichat F, "et al." |title=Clinical and experimental progression of a new model of human prostate cancer and therapeutic approach. |journal=Am. J. Pathol. |volume=159 |issue= 2 |pages= 753–64 |year= 2001 |pmid= 11485933 |doi=
*cite journal | author=Shen WF, Krishnan K, Lawrence HJ, Largman C |title=The HOX homeodomain proteins block CBP histone acetyltransferase activity. |journal=Mol. Cell. Biol. |volume=21 |issue= 21 |pages= 7509–22 |year= 2001 |pmid= 11585930 |doi= 10.1128/MCB.21.21.7509-7522.2001
*cite journal | author=Kosaki K, Kosaki R, Suzuki T, "et al." |title=Complete mutation analysis panel of the 39 human HOX genes. |journal=Teratology |volume=65 |issue= 2 |pages= 50–62 |year= 2002 |pmid= 11857506 |doi= 10.1002/tera.10009
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Hori Y, Gu X, Xie X, Kim SK |title=Differentiation of insulin-producing cells from human neural progenitor cells. |journal=PLoS Med. |volume=2 |issue= 4 |pages= e103 |year= 2006 |pmid= 15839736 |doi= 10.1371/journal.pmed.0020103
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406

External links

*

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