Mesenchyme homeobox 2, also known as MEOX2, is a human gene.cite web | title = Entrez Gene: MEOX2 mesenchyme homeobox 2| url =| accessdate = ]

section_title =
summary_text = This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease.cite web | title = Entrez Gene: MEOX2 mesenchyme homeobox 2| url =| accessdate = ]


Further reading

citations =
*cite journal | author=Grigoriou M, Kastrinaki MC, Modi WS, "et al." |title=Isolation of the human MOX2 homeobox gene and localization to chromosome 7p22.1-p21.3. |journal=Genomics |volume=26 |issue= 3 |pages= 550–5 |year= 1995 |pmid= 7607679 |doi=
*cite journal | author=LePage DF, Altomare DA, Testa JR, Walsh K |title=Molecular cloning and localization of the human GAX gene to 7p21. |journal=Genomics |volume=24 |issue= 3 |pages= 535–40 |year= 1995 |pmid= 7713505 |doi= 10.1006/geno.1994.1663
*cite journal | author=Reardon W, McManus SP, Summers D, Winter RM |title=Cytogenetic evidence that the Saethre-Chotzen gene maps to 7p21.2. |journal=Am. J. Med. Genet. |volume=47 |issue= 5 |pages= 633–6 |year= 1994 |pmid= 8266988 |doi= 10.1002/ajmg.1320470510
*cite journal | author=Quinn LM, Latham SE, Kalionis B |title=The homeobox genes MSX2 and MOX2 are candidates for regulating epithelial-mesenchymal cell interactions in the human placenta. |journal=Placenta |volume=21 Suppl A |issue= |pages= S50–4 |year= 2000 |pmid= 10831122 |doi=
*cite journal | author=Stamataki D, Kastrinaki M, Mankoo BS, "et al." |title=Homeodomain proteins Mox1 and Mox2 associate with Pax1 and Pax3 transcription factors. |journal=FEBS Lett. |volume=499 |issue= 3 |pages= 274–8 |year= 2001 |pmid= 11423130 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Scherer SW, Cheung J, MacDonald JR, "et al." |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423
*cite journal | author=Gorski DH, Leal AJ |title=Inhibition of endothelial cell activation by the homeobox gene Gax. |journal=J. Surg. Res. |volume=111 |issue= 1 |pages= 91–9 |year= 2003 |pmid= 12842453 |doi=
*cite journal | author=Hillier LW, Fulton RS, Fulton LA, "et al." |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Wu Z, Guo H, Chow N, "et al." |title=Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease. |journal=Nat. Med. |volume=11 |issue= 9 |pages= 959–65 |year= 2005 |pmid= 16116430 |doi= 10.1038/nm1287
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Lin J, Friesen MT, Bocangel P, "et al." |title=Characterization of Mesenchyme Homeobox 2 (MEOX2) transcription factor binding to RING finger protein 10. |journal=Mol. Cell. Biochem. |volume=275 |issue= 1-2 |pages= 75–84 |year= 2006 |pmid= 16335786 |doi=
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Chen Y, Leal AD, Patel S, Gorski DH |title=The homeobox gene GAX activates p21WAF1/CIP1 expression in vascular endothelial cells through direct interaction with upstream AT-rich sequences. |journal=J. Biol. Chem. |volume=282 |issue= 1 |pages= 507–17 |year= 2007 |pmid= 17074759 |doi= 10.1074/jbc.M606604200

External links


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