TBX22


TBX22

T-box 22, also known as TBX22, is a human gene.cite web | title = Entrez Gene: TBX22 T-box 22| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50945| accessdate = ]

PBB_Summary
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summary_text = This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis.cite web | title = Entrez Gene: TBX22 T-box 22| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50945| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Laugier-Anfossi F, Villard L |title=Molecular characterization of a new human T-box gene (TBX22) located in xq21.1 encoding a protein containing a truncated T-domain. |journal=Gene |volume=255 |issue= 2 |pages= 289–96 |year= 2000 |pmid= 11024289 |doi=
*cite journal | author=Braybrook C, Doudney K, Marçano AC, "et al." |title=The T-box transcription factor gene TBX22 is mutated in X-linked cleft palate and ankyloglossia. |journal=Nat. Genet. |volume=29 |issue= 2 |pages= 179–83 |year= 2001 |pmid= 11559848 |doi= 10.1038/ng730
*cite journal | author=Aldred MA |title=Cleft lip and palate: new genetic clues. |journal=Trends in molecular medicine |volume=7 |issue= 12 |pages= 539–40 |year= 2002 |pmid= 11733204 |doi=
*cite journal | author=Braybrook C, Lisgo S, Doudney K, "et al." |title=Craniofacial expression of human and murine TBX22 correlates with the cleft palate and ankyloglossia phenotype observed in CPX patients. |journal=Hum. Mol. Genet. |volume=11 |issue= 22 |pages= 2793–804 |year= 2003 |pmid= 12374769 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Marçano AC, Doudney K, Braybrook C, "et al." |title=TBX22 mutations are a frequent cause of cleft palate. |journal=J. Med. Genet. |volume=41 |issue= 1 |pages= 68–74 |year= 2004 |pmid= 14729838 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ross MT, Grafham DV, Coffey AJ, "et al." |title=The DNA sequence of the human X chromosome. |journal=Nature |volume=434 |issue= 7031 |pages= 325–37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440
*cite journal | author=Andreou AM, Pauws E, Jones MC, "et al." |title=TBX22 missense mutations found in patients with X-linked cleft palate affect DNA binding, sumoylation, and transcriptional repression. |journal=Am. J. Hum. Genet. |volume=81 |issue= 4 |pages= 700–12 |year= 2007 |pmid= 17846996 |doi= 10.1086/521033
*cite journal | author=Suphapeetiporn K, Tongkobpetch S, Siriwan P, Shotelersuk V |title=TBX22 mutations are a frequent cause of non-syndromic cleft palate in the Thai population. |journal=Clin. Genet. |volume=72 |issue= 5 |pages= 478–83 |year= 2008 |pmid= 17868388 |doi= 10.1111/j.1399-0004.2007.00891.x

External links

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