HOXA11


HOXA11

Homeobox A11, also known as HOXA11, is a human gene.cite web | title = Entrez Gene: HOXA11 homeobox A11| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3207| accessdate = ]

PBB_Summary
section_title =
summary_text = In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia.cite web | title = Entrez Gene: HOXA11 homeobox A11| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3207| accessdate = ]

ee also

* Homeobox

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Daftary GS, Taylor HS |title=Implantation in the human: the role of HOX genes. |journal=Semin. Reprod. Med. |volume=18 |issue= 3 |pages= 311–20 |year= 2001 |pmid= 11299969 |doi=
*cite journal | author=Daftary GS, Taylor HS |title=Molecular markers of implantation: clinical implications. |journal=Curr. Opin. Obstet. Gynecol. |volume=13 |issue= 3 |pages= 269–74 |year= 2001 |pmid= 11396649 |doi=
*cite journal | author=Davies JA, Fisher CE |title=Genes and proteins in renal development. |journal=Exp. Nephrol. |volume=10 |issue= 2 |pages= 102–13 |year= 2002 |pmid= 11937757 |doi=
*cite journal | author=Eun Kwon H, Taylor HS |title=The role of HOX genes in human implantation. |journal=Ann. N. Y. Acad. Sci. |volume=1034 |issue= |pages= 1–18 |year= 2005 |pmid= 15731295 |doi= 10.1196/annals.1335.001
*cite journal | author=Scott MP |title=Vertebrate homeobox gene nomenclature. |journal=Cell |volume=71 |issue= 4 |pages= 551–3 |year= 1992 |pmid= 1358459 |doi=
*cite journal | author=McAlpine PJ, Shows TB |title=Nomenclature for human homeobox genes. |journal=Genomics |volume=7 |issue= 3 |pages= 460 |year= 1990 |pmid= 1973146 |doi=
*cite journal | author=Acampora D, D'Esposito M, Faiella A, "et al." |title=The human HOX gene family. |journal=Nucleic Acids Res. |volume=17 |issue= 24 |pages= 10385–402 |year= 1990 |pmid= 2574852 |doi=
*cite journal | author=Miano JM, Firulli AB, Olson EN, "et al." |title=Restricted expression of homeobox genes distinguishes fetal from adult human smooth muscle cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 2 |pages= 900–5 |year= 1996 |pmid= 8570656 |doi=
*cite journal | author=Apiou F, Flagiello D, Cillo C, "et al." |title=Fine mapping of human HOX gene clusters. |journal=Cytogenet. Cell Genet. |volume=73 |issue= 1-2 |pages= 114–5 |year= 1996 |pmid= 8646877 |doi=
*cite journal | author=Potter SS, Branford WW |title=Evolutionary conservation and tissue-specific processing of Hoxa 11 antisense transcripts. |journal=Mamm. Genome |volume=9 |issue= 10 |pages= 799–806 |year= 1998 |pmid= 9745033 |doi=
*cite journal | author=Taylor HS, Igarashi P, Olive DL, Arici A |title=Sex steroids mediate HOXA11 expression in the human peri-implantation endometrium. |journal=J. Clin. Endocrinol. Metab. |volume=84 |issue= 3 |pages= 1129–35 |year= 1999 |pmid= 10084606 |doi=
*cite journal | author=Thompson AA, Nguyen LT |title=Amegakaryocytic thrombocytopenia and radio-ulnar synostosis are associated with HOXA11 mutation. |journal=Nat. Genet. |volume=26 |issue= 4 |pages= 397–8 |year= 2001 |pmid= 11101832 |doi= 10.1038/82511
*cite journal | author=Shen WF, Krishnan K, Lawrence HJ, Largman C |title=The HOX homeodomain proteins block CBP histone acetyltransferase activity. |journal=Mol. Cell. Biol. |volume=21 |issue= 21 |pages= 7509–22 |year= 2001 |pmid= 11585930 |doi= 10.1128/MCB.21.21.7509-7522.2001
*cite journal | author=Fujino T, Suzuki A, Ito Y, "et al." |title=Single-translocation and double-chimeric transcripts: detection of NUP98-HOXA9 in myeloid leukemias with HOXA11 or HOXA13 breaks of the chromosomal translocation t(7;11)(p15;p15). |journal=Blood |volume=99 |issue= 4 |pages= 1428–33 |year= 2002 |pmid= 11830496 |doi=
*cite journal | author=Fleischman RA, Letestu R, Mi X, "et al." |title=Absence of mutations in the HoxA10, HoxA11 and HoxD11 nucleotide coding sequences in thrombocytopenia with absent radius syndrome. |journal=Br. J. Haematol. |volume=116 |issue= 2 |pages= 367–75 |year= 2002 |pmid= 11841440 |doi=
*cite journal | author=Kosaki K, Kosaki R, Suzuki T, "et al." |title=Complete mutation analysis panel of the 39 human HOX genes. |journal=Teratology |volume=65 |issue= 2 |pages= 50–62 |year= 2002 |pmid= 11857506 |doi= 10.1002/tera.10009
*cite journal | author=Chau YM, Pando S, Taylor HS |title=HOXA11 silencing and endogenous HOXA11 antisense ribonucleic acid in the uterine endometrium. |journal=J. Clin. Endocrinol. Metab. |volume=87 |issue= 6 |pages= 2674–80 |year= 2002 |pmid= 12050232 |doi=

External links

*

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