FOXN3


FOXN3

Checkpoint suppressor 1, also known as CHES1, is a human gene.cite web | title = Entrez Gene: CHES1 checkpoint suppressor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1112| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms.cite web | title = Entrez Gene: CHES1 checkpoint suppressor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1112| accessdate = ]

ee also

* FOX proteins

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Field LL, Tobias R, Thomson G, Plon S |title=Susceptibility to insulin-dependent diabetes mellitus maps to a locus (IDDM11) on human chromosome 14q24.3-q31. |journal=Genomics |volume=33 |issue= 1 |pages= 1–8 |year= 1996 |pmid= 8617492 |doi= 10.1006/geno.1996.0153
*cite journal | author=Hillier LD, Lennon G, Becker M, "et al." |title=Generation and analysis of 280,000 human expressed sequence tags. |journal=Genome Res. |volume=6 |issue= 9 |pages= 807–28 |year= 1997 |pmid= 8889549 |doi=
*cite journal | author=Pati D, Keller C, Groudine M, Plon SE |title=Reconstitution of a MEC1-independent checkpoint in yeast by expression of a novel human fork head cDNA. |journal=Mol. Cell. Biol. |volume=17 |issue= 6 |pages= 3037–46 |year= 1997 |pmid= 9154802 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Yu Y, Zhang C, Zhou G, "et al." |title=Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs. |journal=Genome Res. |volume=11 |issue= 8 |pages= 1392–403 |year= 2001 |pmid= 11483580 |doi= 10.1101/gr.175501
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Heilig R, Eckenberg R, Petit JL, "et al." |title=The DNA sequence and analysis of human chromosome 14. |journal=Nature |volume=421 |issue= 6923 |pages= 601–7 |year= 2003 |pmid= 12508121 |doi= 10.1038/nature01348
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Lehner B, Sanderson CM |title=A protein interaction framework for human mRNA degradation. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1315–23 |year= 2004 |pmid= 15231747 |doi= 10.1101/gr.2122004
*cite journal | author=Suzuki Y, Yamashita R, Shirota M, "et al." |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Scott KL, Plon SE |title=CHES1/FOXN3 interacts with Ski-interacting protein and acts as a transcriptional repressor. |journal=Gene |volume=359 |issue= |pages= 119–26 |year= 2005 |pmid= 16102918 |doi= 10.1016/j.gene.2005.06.014
*cite journal | author=Busygina V, Kottemann MC, Scott KL, "et al." |title=Multiple endocrine neoplasia type 1 interacts with forkhead transcription factor CHES1 in DNA damage response. |journal=Cancer Res. |volume=66 |issue= 17 |pages= 8397–403 |year= 2007 |pmid= 16951149 |doi= 10.1158/0008-5472.CAN-06-0061
*cite journal | author=Katoh H, Ojima H, Kokubu A, "et al." |title=Genetically distinct and clinically relevant classification of hepatocellular carcinoma: putative therapeutic targets. |journal=Gastroenterology |volume=133 |issue= 5 |pages= 1475–86 |year= 2007 |pmid= 17983802 |doi= 10.1053/j.gastro.2007.08.038

External links

*

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Look at other dictionaries:

  • FOX proteins — FOX (Forkhead box) proteins are a family of transcription factors that play important roles in regulating the expression of genes involved in cell growth, proliferation, differentiation, and longevity. Many FOX proteins are important to embryonic …   Wikipedia

  • FOX-Gen — Die Forkhead Box, Abkürzung FOX, ist ein charakteristischer DNA Abschnitt, der in vielen Genen auftritt. Alle Gene, die diese Nukleotidsequenz enthalten, werden zu der Familie der Forkhead Box Gene gerechnet.[1] Die Forkhead Box Gene sind eine… …   Deutsch Wikipedia

  • FOX-Protein — Die Forkhead Box, Abkürzung FOX, ist ein charakteristischer DNA Abschnitt, der in vielen Genen auftritt. Alle Gene, die diese Nukleotidsequenz enthalten, werden zu der Familie der Forkhead Box Gene gerechnet.[1] Die Forkhead Box Gene sind eine… …   Deutsch Wikipedia

  • Forkhead — Die Forkhead Box, Abkürzung FOX, ist ein charakteristischer DNA Abschnitt, der in vielen Genen auftritt. Alle Gene, die diese Nukleotidsequenz enthalten, werden zu der Familie der Forkhead Box Gene gerechnet.[1] Die Forkhead Box Gene sind eine… …   Deutsch Wikipedia

  • Forkhead-Box — Die Forkhead Box, Abkürzung FOX, ist ein charakteristischer DNA Abschnitt, der in vielen Genen auftritt. Alle Gene, die diese Nukleotidsequenz enthalten, werden zu der Familie der Forkhead Box Gene gerechnet.[1] Die Forkhead Box Gene sind eine… …   Deutsch Wikipedia

  • Forkhead-Box-Gen — Die Forkhead Box, Abkürzung FOX, ist ein charakteristischer DNA Abschnitt, der in vielen Genen auftritt. Alle Gene, die diese Nukleotidsequenz enthalten, werden zu der Familie der Forkhead Box Gene gerechnet.[1] Die Forkhead Box Gene sind eine… …   Deutsch Wikipedia

  • Forkhead-Gen — Die Forkhead Box, Abkürzung FOX, ist ein charakteristischer DNA Abschnitt, der in vielen Genen auftritt. Alle Gene, die diese Nukleotidsequenz enthalten, werden zu der Familie der Forkhead Box Gene gerechnet.[1] Die Forkhead Box Gene sind eine… …   Deutsch Wikipedia

  • Forkhead-Protein — Die Forkhead Box, Abkürzung FOX, ist ein charakteristischer DNA Abschnitt, der in vielen Genen auftritt. Alle Gene, die diese Nukleotidsequenz enthalten, werden zu der Familie der Forkhead Box Gene gerechnet.[1] Die Forkhead Box Gene sind eine… …   Deutsch Wikipedia

  • Forkhead-Box-Proteine — Bändermodell des FOXO4 Protein DNA Komplexes nach PDB 3BPY Die Forkhead Box Proteine (FOX) sind Proteine in Eukaryoten, die sich im Zellkern an bestimmte Stellen der DNA heften und dadurch die Transkription von …   Deutsch Wikipedia


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.