Activating protein 2


Activating protein 2

protein
Name = transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)


width =
caption =
Symbol = TFAP2A
AltSymbols = TFAP2, AP2TF
ATC_prefix=
ATC_suffix=
ATC_supplemental=
CAS_number=
CAS_supplemental=
DrugBank=
EntrezGene = 7020
HGNCid = 11742
OMIM = 107580
PDB =
RefSeq = NM_003220
UniProt = P05549
ECnumber =
Chromosome = 6
Arm = p
Band = 22.3
LocusSupplementaryData =

protein
Name = transcription factor AP-2 beta (activating enhancer binding protein 2 beta)


width =
caption =
Symbol = TFAP2B
AltSymbols = AP2-B
ATC_prefix=
ATC_suffix=
ATC_supplemental=
CAS_number=
CAS_supplemental=
DrugBank=
EntrezGene = 7021
HGNCid = 11743
OMIM = 601601
PDB =
RefSeq = NM_003221
UniProt = Q92481
ECnumber =
Chromosome = 6
Arm = p
Band = 12
LocusSupplementaryData =

protein
Name = transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)


width =
caption =
Symbol = TFAP2C
AltSymbols =
ATC_prefix=
ATC_suffix=
ATC_supplemental=
CAS_number=
CAS_supplemental=
DrugBank=
EntrezGene = 7022
HGNCid = 11744
OMIM = 601602
PDB =
RefSeq = NM_003222
UniProt = Q92754
ECnumber =
Chromosome = 20
Arm = q
Band = 13.2
LocusSupplementaryData =

protein
Name = transcription factor AP-2 delta (activating enhancer binding protein 2 delta)


width =
caption =
Symbol = TFAP2D
AltSymbols = TFAP2BL1
ATC_prefix=
ATC_suffix=
ATC_supplemental=
CAS_number=
CAS_supplemental=
DrugBank=
EntrezGene = 83741
HGNCid = 15581
OMIM = 610161
PDB =
RefSeq = NM_172238
UniProt = Q7Z6R9
ECnumber =
Chromosome = 6
Arm = p
Band = 12.3
LocusSupplementaryData =

protein
Name = transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)


width =
caption =
Symbol = TFAP2E
AltSymbols = AP2E
ATC_prefix=
ATC_suffix=
ATC_supplemental=
CAS_number=
CAS_supplemental=
DrugBank=
EntrezGene = 339488
HGNCid = 30774
OMIM =
PDB =
RefSeq = NM_178548
UniProt = Q6VUC0
ECnumber =
Chromosome = 1
Arm = p
Band = 34.3
LocusSupplementaryData =

Activating Protein 2 (AP-2) is a family of closely related transcription factorscite journal |author=Williams T, Tjian R |title=Characterization of a dimerization motif in AP-2 and its function in heterologous DNA-binding proteins |journal=Science |volume=251 |issue=4997 |pages=1067–71 |year=1991 |pmid=1998122 |doi= 10.1126/science.1998122 |issn=] cite journal |author=Williams T, Tjian R |title=Analysis of the DNA-binding and activation properties of the human transcription factor AP-2 |journal=Genes Dev. |volume=5 |issue=4 |pages=670–82 |year=1991 |pmid=2010091 |doi= 10.1101/gad.5.4.670 |issn=] which plays a critical role in regulating gene expression during early development.cite journal |author=Hilger-Eversheim K, Moser M, Schorle H, Buettner R |title=Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control |journal=Gene |volume=260 |issue=1-2 |pages=1–12 |year=2000 |pmid=11137286 |doi= 10.1016/S0378-1119(00)00454-6 |issn=]

References

External links

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