Spi-B transcription factor (Spi-1/PU.1 related), also known as SPIB, is a human gene.cite web | title = Entrez Gene: SPIB Spi-B transcription factor (Spi-1/PU.1 related)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6689| accessdate = ]

section_title =
summary_text = SPI1 (MIM 165170) and SPIB are members of a subfamily of ETS (see ETS1; MIM 164720) transcription factors. ETS proteins share a conserved ETS domain that mediates specific DNA binding. SPIB and SPI1 bind to a purine-rich sequence, the PU box (5-prime-GAGGAA-3-prime). [supplied by OMIM] cite web | title = Entrez Gene: SPIB Spi-B transcription factor (Spi-1/PU.1 related)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6689| accessdate = ]


Further reading

citations =
*cite journal | author=Ray D, Bosselut R, Ghysdael J, "et al." |title=Characterization of Spi-B, a transcription factor related to the putative oncoprotein Spi-1/PU.1. |journal=Mol. Cell. Biol. |volume=12 |issue= 10 |pages= 4297–304 |year= 1992 |pmid= 1406622 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Mao C, Ray-Gallet D, Tavitian A, Moreau-Gachelin F |title=Differential phosphorylations of Spi-B and Spi-1 transcription factors. |journal=Oncogene |volume=12 |issue= 4 |pages= 863–73 |year= 1996 |pmid= 8632909 |doi=
*cite journal | author=Ray-Gallet D, Tavitian A, Moreau-Gachelin F |title=An alternatively spliced isoform of the Spi-B transcription factor. |journal=Biochem. Biophys. Res. Commun. |volume=223 |issue= 2 |pages= 257–63 |year= 1996 |pmid= 8670269 |doi= 10.1006/bbrc.1996.0881
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Rao S, Matsumura A, Yoon J, Simon MC |title=SPI-B activates transcription via a unique proline, serine, and threonine domain and exhibits DNA binding affinity differences from PU.1. |journal=J. Biol. Chem. |volume=274 |issue= 16 |pages= 11115–24 |year= 1999 |pmid= 10196196 |doi=
*cite journal | author=Nagy M, Chapuis B, Matthes T |title=Expression of transcription factors Pu.1, Spi-B, Blimp-1, BSAP and oct-2 in normal human plasma cells and in multiple myeloma cells. |journal=Br. J. Haematol. |volume=116 |issue= 2 |pages= 429–35 |year= 2002 |pmid= 11841448 |doi=
*cite journal | author=Yamamoto H, Kihara-Negishi F, Yamada T, "et al." |title=Interaction between the hematopoietic Ets transcription factor Spi-B and the coactivator CREB-binding protein associated with negative cross-talk with c-Myb. |journal=Cell Growth Differ. |volume=13 |issue= 2 |pages= 69–75 |year= 2002 |pmid= 11864910 |doi=
*cite journal | author=Schotte R, Rissoan MC, Bendriss-Vermare N, "et al." |title=The transcription factor Spi-B is expressed in plasmacytoid DC precursors and inhibits T-, B-, and NK-cell development. |journal=Blood |volume=101 |issue= 3 |pages= 1015–23 |year= 2003 |pmid= 12393575 |doi= 10.1182/blood-2002-02-0438
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Schotte R, Nagasawa M, Weijer K, "et al." |title=The ETS transcription factor Spi-B is required for human plasmacytoid dendritic cell development. |journal=J. Exp. Med. |volume=200 |issue= 11 |pages= 1503–9 |year= 2005 |pmid= 15583020 |doi= 10.1084/jem.20041231
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Geng CD, Vedeckis WV |title=c-Myb and members of the c-Ets family of transcription factors act as molecular switches to mediate opposite steroid regulation of the human glucocorticoid receptor 1A promoter. |journal=J. Biol. Chem. |volume=280 |issue= 52 |pages= 43264–71 |year= 2006 |pmid= 16263717 |doi= 10.1074/jbc.M508245200
*cite journal | author=Dontje W, Schotte R, Cupedo T, "et al." |title=Delta-like1-induced Notch1 signaling regulates the human plasmacytoid dendritic cell versus T-cell lineage decision through control of GATA-3 and Spi-B. |journal=Blood |volume=107 |issue= 6 |pages= 2446–52 |year= 2006 |pmid= 16317090 |doi= 10.1182/blood-2005-05-2090

External links


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