HOXB1


HOXB1

Homeobox B1, also known as HOXB1, is a human gene.cite web | title = Entrez Gene: HOXB1 homeobox B1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3211| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17.cite web | title = Entrez Gene: HOXB1 homeobox B1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3211| accessdate = ]

ee also

* Homeobox

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Scott MP |title=Vertebrate homeobox gene nomenclature. |journal=Cell |volume=71 |issue= 4 |pages= 551–3 |year= 1992 |pmid= 1358459 |doi=
*cite journal | author=McAlpine PJ, Shows TB |title=Nomenclature for human homeobox genes. |journal=Genomics |volume=7 |issue= 3 |pages= 460 |year= 1990 |pmid= 1973146 |doi=
*cite journal | author=Acampora D, D'Esposito M, Faiella A, "et al." |title=The human HOX gene family. |journal=Nucleic Acids Res. |volume=17 |issue= 24 |pages= 10385–402 |year= 1990 |pmid= 2574852 |doi=
*cite journal | author=Boncinelli E, Acampora D, Pannese M, "et al." |title=Organization of human class I homeobox genes. |journal=Genome |volume=31 |issue= 2 |pages= 745–56 |year= 1990 |pmid= 2576652 |doi=
*cite journal | author=Guazzi S, Lonigro R, Pintonello L, "et al." |title=The thyroid transcription factor-1 gene is a candidate target for regulation by Hox proteins. |journal=EMBO J. |volume=13 |issue= 14 |pages= 3339–47 |year= 1994 |pmid= 7913891 |doi=
*cite journal | author=Miano JM, Firulli AB, Olson EN, "et al." |title=Restricted expression of homeobox genes distinguishes fetal from adult human smooth muscle cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 2 |pages= 900–5 |year= 1996 |pmid= 8570656 |doi=
*cite journal | author=Apiou F, Flagiello D, Cillo C, "et al." |title=Fine mapping of human HOX gene clusters. |journal=Cytogenet. Cell Genet. |volume=73 |issue= 1-2 |pages= 114–5 |year= 1996 |pmid= 8646877 |doi=
*cite journal | author=Berthelsen J, Zappavigna V, Ferretti E, "et al." |title=The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity. |journal=EMBO J. |volume=17 |issue= 5 |pages= 1434–45 |year= 1998 |pmid= 9482740 |doi= 10.1093/emboj/17.5.1434
*cite journal | author=Piper DE, Batchelor AH, Chang CP, "et al." |title=Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation. |journal=Cell |volume=96 |issue= 4 |pages= 587–97 |year= 1999 |pmid= 10052460 |doi=
*cite journal | author=Jungbluth S, Bell E, Lumsden A |title=Specification of distinct motor neuron identities by the singular activities of individual Hox genes. |journal=Development |volume=126 |issue= 12 |pages= 2751–8 |year= 1999 |pmid= 10331985 |doi=
*cite journal | author=Jacobs Y, Schnabel CA, Cleary ML |title=Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity. |journal=Mol. Cell. Biol. |volume=19 |issue= 7 |pages= 5134–42 |year= 1999 |pmid= 10373562 |doi=
*cite journal | author=Faiella A, Zortea M, Barbaria E, "et al." |title=A genetic polymorphism in the human HOXB1 homeobox gene implying a 9bp tandem repeat in the amino-terminal coding region. Mutations in brief no. 200. Online. |journal=Hum. Mutat. |volume=12 |issue= 5 |pages= 363 |year= 2000 |pmid= 10671062 |doi=
*cite journal | author=Mikkola I, Bruun JA, Holm T, Johansen T |title=Superactivation of Pax6-mediated transactivation from paired domain-binding sites by dna-independent recruitment of different homeodomain proteins. |journal=J. Biol. Chem. |volume=276 |issue= 6 |pages= 4109–18 |year= 2001 |pmid= 11069920 |doi= 10.1074/jbc.M008882200
*cite journal | author=Ingram JL, Stodgell CJ, Hyman SL, "et al." |title=Discovery of allelic variants of HOXA1 and HOXB1: genetic susceptibility to autism spectrum disorders. |journal=Teratology |volume=62 |issue= 6 |pages= 393–405 |year= 2001 |pmid= 11091361 |doi= 10.1002/1096-9926(200012)62:6<393::AID-TERA6>3.0.CO;2-V |doilabel=10.1002/1096-9926(200012)62:6393::AID-TERA63.0.CO;2-V
*cite journal | author=Di Rocco G, Gavalas A, Popperl H, "et al." |title=The recruitment of SOX/OCT complexes and the differential activity of HOXA1 and HOXB1 modulate the Hoxb1 auto-regulatory enhancer function. |journal=J. Biol. Chem. |volume=276 |issue= 23 |pages= 20506–15 |year= 2001 |pmid= 11278854 |doi= 10.1074/jbc.M011175200
*cite journal | author=Li J, Tabor HK, Nguyen L, "et al." |title=Lack of association between HoxA1 and HoxB1 gene variants and autism in 110 multiplex families. |journal=Am. J. Med. Genet. |volume=114 |issue= 1 |pages= 24–30 |year= 2002 |pmid= 11840501 |doi=
*cite journal | author=Kosaki K, Kosaki R, Suzuki T, "et al." |title=Complete mutation analysis panel of the 39 human HOX genes. |journal=Teratology |volume=65 |issue= 2 |pages= 50–62 |year= 2002 |pmid= 11857506 |doi= 10.1002/tera.10009
*cite journal | author=Fognani C, Kilstrup-Nielsen C, Berthelsen J, "et al." |title=Characterization of PREP2, a paralog of PREP1, which defines a novel sub-family of the MEINOX TALE homeodomain transcription factors. |journal=Nucleic Acids Res. |volume=30 |issue= 9 |pages= 2043–51 |year= 2002 |pmid= 11972344 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Subramaniam N, Campión J, Rafter I, Okret S |title=Cross-talk between glucocorticoid and retinoic acid signals involving glucocorticoid receptor interaction with the homoeodomain protein Pbx1. |journal=Biochem. J. |volume=370 |issue= Pt 3 |pages= 1087–95 |year= 2003 |pmid= 12487626 |doi= 10.1042/BJ20020471

External links

*

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