RFX3


RFX3

Regulatory factor X, 3 (influences HLA class II expression), also known as RFX3, is a human gene.cite web | title = Entrez Gene: RFX3 regulatory factor X, 3 (influences HLA class II expression)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5991| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Two transcript variants encoding different isoforms have been described for this gene, and at least one of the variants utilizes alternative polyadenylation signals.cite web | title = Entrez Gene: RFX3 regulatory factor X, 3 (influences HLA class II expression)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5991| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Reith W, Ucla C, Barras E, "et al." |title=RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins. |journal=Mol. Cell. Biol. |volume=14 |issue= 2 |pages= 1230–44 |year= 1994 |pmid= 8289803 |doi=
*cite journal | author=Emery P, Durand B, Mach B, Reith W |title=RFX proteins, a novel family of DNA binding proteins conserved in the eukaryotic kingdom. |journal=Nucleic Acids Res. |volume=24 |issue= 5 |pages= 803–7 |year= 1996 |pmid= 8600444 |doi=
*cite journal | author=Iwama A, Pan J, Zhang P, "et al." |title=Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains. |journal=Mol. Cell. Biol. |volume=19 |issue= 6 |pages= 3940–50 |year= 1999 |pmid= 10330134 |doi=
*cite journal | author=Morotomi-Yano K, Yano K, Saito H, "et al." |title=Human regulatory factor X 4 (RFX4) is a testis-specific dimeric DNA-binding protein that cooperates with other human RFX members. |journal=J. Biol. Chem. |volume=277 |issue= 1 |pages= 836–42 |year= 2002 |pmid= 11682486 |doi= 10.1074/jbc.M108638200
*cite journal | author=Nakayama A, Murakami H, Maeyama N, "et al." |title=Role for RFX transcription factors in non-neuronal cell-specific inactivation of the microtubule-associated protein MAP1A promoter. |journal=J. Biol. Chem. |volume=278 |issue= 1 |pages= 233–40 |year= 2003 |pmid= 12411430 |doi= 10.1074/jbc.M209574200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Maijgren S, Sur I, Nilsson M, Toftgård R |title=Involvement of RFX proteins in transcriptional activation from a Ras-responsive enhancer element. |journal=Arch. Dermatol. Res. |volume=295 |issue= 11 |pages= 482–9 |year= 2004 |pmid= 15024578 |doi= 10.1007/s00403-004-0456-5
*cite journal | author=Humphray SJ, Oliver K, Hunt AR, "et al." |title=DNA sequence and analysis of human chromosome 9. |journal=Nature |volume=429 |issue= 6990 |pages= 369–74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209

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