Endothelial PAS domain protein 1, also known as EPAS1, is a human gene. [cite web | title = Entrez Gene: EPAS1 endothelial PAS domain protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2034| accessdate = ]

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Further reading

citations =
*cite journal | author=Brahimi-Horn MC, Pouysségur J |title=The hypoxia-inducible factor and tumor progression along the angiogenic pathway. |journal=Int. Rev. Cytol. |volume=242 |issue= |pages= 157–213 |year= 2005 |pmid= 15598469 |doi= 10.1016/S0074-7696(04)42004-X
*cite journal | author=Haase VH |title=Hypoxia-inducible factors in the kidney. |journal=Am. J. Physiol. Renal Physiol. |volume=291 |issue= 2 |pages= F271–81 |year= 2006 |pmid= 16554418 |doi= 10.1152/ajprenal.00071.2006
*cite journal | author=Andersson B, Wentland MA, Ricafrente JY, "et al." |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138
*cite journal | author=Tian H, McKnight SL, Russell DW |title=Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. |journal=Genes Dev. |volume=11 |issue= 1 |pages= 72–82 |year= 1997 |pmid= 9000051 |doi=
*cite journal | author=Hogenesch JB, Chan WK, Jackiw VH, "et al." |title=Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway. |journal=J. Biol. Chem. |volume=272 |issue= 13 |pages= 8581–93 |year= 1997 |pmid= 9079689 |doi=
*cite journal | author=Yu W, Andersson B, Worley KC, "et al." |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=
*cite journal | author=Ema M, Taya S, Yokotani N, "et al." |title=A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 9 |pages= 4273–8 |year= 1997 |pmid= 9113979 |doi=
*cite journal | author=Hogenesch JB, Gu YZ, Jain S, Bradfield CA |title=The basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 10 |pages= 5474–9 |year= 1998 |pmid= 9576906 |doi=
*cite journal | author=Takahata S, Sogawa K, Kobayashi A, "et al." |title=Transcriptionally active heterodimer formation of an Arnt-like PAS protein, Arnt3, with HIF-1a, HLF, and clock. |journal=Biochem. Biophys. Res. Commun. |volume=248 |issue= 3 |pages= 789–94 |year= 1998 |pmid= 9704006 |doi= 10.1006/bbrc.1998.9012
*cite journal | author=Ema M, Hirota K, Mimura J, "et al." |title=Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300. |journal=EMBO J. |volume=18 |issue= 7 |pages= 1905–14 |year= 1999 |pmid= 10202154 |doi= 10.1093/emboj/18.7.1905
*cite journal | author=Cockman ME, Masson N, Mole DR, "et al." |title=Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein. |journal=J. Biol. Chem. |volume=275 |issue= 33 |pages= 25733–41 |year= 2000 |pmid= 10823831 |doi= 10.1074/jbc.M002740200
*cite journal | author=Maemura K, de la Monte SM, Chin MT, "et al." |title=CLIF, a novel cycle-like factor, regulates the circadian oscillation of plasminogen activator inhibitor-1 gene expression. |journal=J. Biol. Chem. |volume=275 |issue= 47 |pages= 36847–51 |year= 2001 |pmid= 11018023 |doi= 10.1074/jbc.C000629200
*cite journal | author=Luo JC, Shibuya M |title=A variant of nuclear localization signal of bipartite-type is required for the nuclear translocation of hypoxia inducible factors (1alpha, 2alpha and 3alpha). |journal=Oncogene |volume=20 |issue= 12 |pages= 1435–44 |year= 2001 |pmid= 11313887 |doi= 10.1038/sj.onc.1204228
*cite journal | author=Woods SL, Whitelaw ML |title=Differential activities of murine single minded 1 (SIM1) and SIM2 on a hypoxic response element. Cross-talk between basic helix-loop-helix/per-Arnt-Sim homology transcription factors. |journal=J. Biol. Chem. |volume=277 |issue= 12 |pages= 10236–43 |year= 2002 |pmid= 11782478 |doi= 10.1074/jbc.M110752200
*cite journal | author=Lando D, Peet DJ, Whelan DA, "et al." |title=Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch. |journal=Science |volume=295 |issue= 5556 |pages= 858–61 |year= 2002 |pmid= 11823643 |doi= 10.1126/science.1068592
*cite journal | author=Mole DR, Pugh CW, Ratcliffe PJ, Maxwell PH |title=Regulation of the HIF pathway: enzymatic hydroxylation of a conserved prolyl residue in hypoxia-inducible factor alpha subunits governs capture by the pVHL E3 ubiquitin ligase complex. |journal=Adv. Enzyme Regul. |volume=42 |issue= |pages= 333–47 |year= 2002 |pmid= 12123724 |doi=
*cite journal | author=Sivridis E, Giatromanolaki A, Gatter KC, "et al." |title=Association of hypoxia-inducible factors 1alpha and 2alpha with activated angiogenic pathways and prognosis in patients with endometrial carcinoma. |journal=Cancer |volume=95 |issue= 5 |pages= 1055–63 |year= 2002 |pmid= 12209691 |doi= 10.1002/cncr.10774
*cite journal | author=Elvert G, Kappel A, Heidenreich R, "et al." |title=Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha ) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1). |journal=J. Biol. Chem. |volume=278 |issue= 9 |pages= 7520–30 |year= 2003 |pmid= 12464608 |doi= 10.1074/jbc.M211298200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Sang N, Stiehl DP, Bohensky J, "et al." |title=MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300. |journal=J. Biol. Chem. |volume=278 |issue= 16 |pages= 14013–9 |year= 2003 |pmid= 12588875 |doi= 10.1074/jbc.M209702200

External links


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