PASK

PASK
PAS domain containing serine/threonine kinase

PDB rendering based on 1ll8.
Identifiers
Symbols PASK; DKFZp434O051; DKFZp686P2031; KIAA0135; PASKIN; STK37
External IDs OMIM607505 MGI2155936 HomoloGene9038 GeneCards: PASK Gene
EC number 2.7.11.1
RNA expression pattern
PBB GE PASK 213534 s at tn.png
PBB GE PASK 216945 x at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 23178 269224
Ensembl ENSG00000115687 ENSMUSG00000026274
UniProt Q96RG2 Q8CEE6
RefSeq (mRNA) NM_015148 NM_080850.2
RefSeq (protein) NP_055963 NP_543126.2
Location (UCSC) Chr 2:
242.05 – 242.09 Mb
Chr 1:
95.21 – 95.24 Mb
PubMed search [1] [2]

PAS domain-containing serine/threonine-protein kinase is an enzyme that in humans is encoded by the PASK gene.[1][2][3][4]

PAS domains regulate the function of many intracellular signaling pathways in response to both extrinsic and intrinsic stimuli. PASK is an evolutionarily conserved protein present in yeast, flies, and mammals.[supplied by OMIM][4]

References

  1. ^ Hofer T, Spielmann P, Stengel P, Stier B, Katschinski DM, Desbaillets I, Gassmann M, Wenger RH (Nov 2001). "Mammalian PASKIN, a PAS-serine/threonine kinase related to bacterial oxygen sensors". Biochem Biophys Res Commun 288 (4): 757–64. doi:10.1006/bbrc.2001.5840. PMID 11688972. 
  2. ^ Rutter J, Michnoff CH, Harper SM, Gardner KH, McKnight SL (Aug 2001). "PAS kinase: an evolutionarily conserved PAS domain-regulated serine/threonine kinase". Proc Natl Acad Sci U S A 98 (16): 8991–6. doi:10.1073/pnas.161284798. PMC 55361. PMID 11459942. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=55361. 
  3. ^ da Silva Xavier G, Rutter J, Rutter GA (Jun 2004). "Involvement of Per-Arnt-Sim (PAS) kinase in the stimulation of preproinsulin and pancreatic duodenum homeobox 1 gene expression by glucose". Proc Natl Acad Sci U S A 101 (22): 8319–24. doi:10.1073/pnas.0307737101. PMC 420392. PMID 15148392. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=420392. 
  4. ^ a b "Entrez Gene: PASK PAS domain containing serine/threonine kinase". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23178. 

Further reading



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  • Pask — Andrew Gordon Speedie Pask (* 28. Juni 1928 in Derby; † 29. März 1996 in London) war ein bedeutender englischer Kybernetiker und Psychologe. Von 1976 bis 1979 war er Vorsitzender der britischen Gesellschaft für Kybernetik. Weblinks Eintrag zu… …   Deutsch Wikipedia

  • Pask — recorded in several forms as shown below, this unusual and interesting name is of Old French origins. Introduced into England by the Norman French after the famous Conquest of 1066, it derives from the words pasche or pasque, meaning Easter. In… …   Surnames reference

  • pask — 3 pàsk praep. su acc. žr. 3 paskui 1: Vaikai pask motiną bėga Grž. Bernas pàsk mergas sekioja Jnšk. Norėjo sekt pàsk poną savo BM126. | Ir duktė numirė pask tėvą Ps …   Dictionary of the Lithuanian Language

  • pask — Easter Eas ter ([=e]s t[ e]r), n. [AS. e[ a]ster, e[ a]stran, paschal feast, Easter; akin to G. ostern; fr. AS. E[ a]stre, a goddess of light or spring, in honor of whom a festival was celebrated in April; whence this month was called in AS. E[… …   The Collaborative International Dictionary of English

  • påsk — • påskveckan • påsktiden …   Svensk synonymlexikon

  • pask — 1 pàsk adv., pãsk žr. 1 paskui 2: Po davatkyną gyvenau, pàsk išejau pry žmonių Grd. Pàsk rašė, ka važiuos numien Šv. Buvo spuogas, pàsk pranyko Vn. Penkios trobelės buvo, pàsk dalijo sklypais tokiais Pj. Pãsk ateis ant mislės BM119 …   Dictionary of the Lithuanian Language

  • pask — 2 pãsk adv. žr. 2 paskui: Pãsk sekdavo, kad nepamatyč gyvatės LKKV160 …   Dictionary of the Lithuanian Language

  • påsk — s ( en, ar) …   Clue 9 Svensk Ordbok

  • päsk — s ( en, ar) KLÄD renskinnspäls …   Clue 9 Svensk Ordbok

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