P2RY14

P2RY14
Purinergic receptor P2Y, G-protein coupled, 14
Identifiers
Symbols P2RY14; GPR105; KIAA0001; P2Y14
External IDs OMIM610116 MGI2155705 HomoloGene15769 GeneCards: P2RY14 Gene
RNA expression pattern
PBB GE P2RY14 206637 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 9934 140795
Ensembl ENSG00000174944 ENSMUSG00000036381
UniProt Q15391 Q544F4
RefSeq (mRNA) NM_001081455.1 NM_001008497
RefSeq (protein) NP_001074924.1 NP_001008497
Location (UCSC) Chr 3:
150.93 – 151 Mb
Chr 3:
58.92 – 58.93 Mb
PubMed search [1] [2]

P2Y purinoceptor 14 is a protein that in humans is encoded by the P2RY14 gene.[1]

The product of this gene, P2Y14 belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene.[1]

Contents

See also

References

Further reading

Metabolites and
signaling molecules
Peptide
Miscellaneous
Class B: Secretin like Class C: Metabotropic
glutamate / pheromone Class F:
Frizzled / Smoothened B trdu: iter (nrpl/grfl/cytl/horl), csrc (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd; path (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)

External links


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Look at other dictionaries:

  • P2Y receptor — P2Y receptors are a family of purinergic receptors, G protein coupled receptors stimulated by nucleotides such as ATP, ADP, UTP, UDP and UDP glucose. To date, 12 P2Y receptors have been cloned in humans: P2Y1, P2Y2, P2Y4, P2Y5, P2Y6, P2Y8, P2Y9… …   Wikipedia

  • Rhodopsin-like receptors — Pfam box Symbol = 7tm 1 Name = Rhodopsin like receptors width = caption = Pfam= PF00001 InterPro= IPR000276 SMART= PROSITE = PDOC00211 SCOP = 1f88 TCDB = OPM family= 6 OPM protein= 1gzm PDB=Rhodopsin like receptors are the largest group of G… …   Wikipedia

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