Methoxetamine Systematic (IUPAC) name (RS)2-(3-methoxyphenyl)-2-(ethylamino)cyclohexanone Clinical data Pregnancy cat. ? Legal status ? Identifiers CAS number ATC code None ChemSpider Chemical data Formula C15H21NO2 Mol. mass 247.33 g/mol SMILES & (what is this?)
Methoxetamine (MXE) or 3-MeO-2-Oxo-PCE is a chemical of the arylcyclohexylamine class which has been sold as a designer drug. It is a derivative of ketamine that also contains structural features of eticyclidine and 3-MeO-PCP. Methoxetamine is thought to behave as a NMDA receptor antagonist and dopamine reuptake inhibitor, though it has not been formally profiled pharmacologically. Methoxetamine differs from many other dissociative anesthetics of the arylcyclohexylamine class in that it was designed for grey-market distribution. Methoxetamine is a product of rational drug design: its N-ethyl group was chosen to increase potency, lessening the risk of interstitial cystitis that can result from the accumulation of ketamine-like metabolites in the urinary bladder.
- ^ EMCDDA Annual Report 2010
- ^ Ward, J.; Rhyee, S.; Plansky, J. (2011). "Methoxetamine: A novel ketamine analog and growing health-care concern". Clinical Toxicology: 1. doi:10.3109/15563650.2011.617310.
- ^ a b , Morris, H. (11 February 2011). "Interview with a ketamine chemist: or to be more precise, an arylcyclohexylamine chemist". Vice Magazine. Retrieved 2011-02-11.
- ^ "4-Amino-4-arylcyclohexanones and Their Derivatives, a Novel Class of Analgesics. 1. Modification of the Aryl Ring." Daniel Lednicer, Philip F. VonVoigtlander and D. Edward Emmert. The Upjohn Company, Research Laboratories, Kalamazoo, Michigan 49001. Received August 7, 1979. J. Med. Chem 1980, 23, p424-430
Wikimedia Foundation. 2010.
Look at other dictionaries:
Arylcyclohexylamine — Phencyclidine, the prototypal arylcyclohexylamine derivative. Arylcyclohexylamines, also known as arylcyclohexamines or arylcyclohexanamines, are a chemical class of pharmaceutical, designer, and experimental drugs. Contents … Wikipedia
Phencyclidine — Systematic (IUPAC) name … Wikipedia
Nitrous oxide — N2O redirects here. For other uses, see N2O (disambiguation). Laughing gas redirects here. For other uses, see Laughing gas (disambiguation). Not to be confused with nitric oxide (formula NO) or nitrogen dioxide (formula NO2). For other uses, see … Wikipedia
Designer drug — Not to be confused with Drug design. Designer drug is a term used to describe drugs that are created (or marketed, if they had already existed) to get around existing drug laws, usually by preparing analogs or derivatives of existing drugs by… … Wikipedia
Dextrorphan — Systematic (IUPAC) name (+) 17 methyl 9a,13a,14a morphinan 3 ol … Wikipedia
Dextromethorphan — Not to be confused with Dexamethasone. Dextromethorphan Systematic (IUP … Wikipedia
Dissociative — See dissociation for the dissociative state in psychology. For the Australian band, see The Dissociatives. Dissociatives are a class of psychoactive drugs which are said to reduce or block signals to the conscious mind from other parts of the… … Wikipedia
Dimethyltryptamine — Systematic (IUPAC) name 2 (1H indol 3 yl) N … Wikipedia
Lysergic acid diethylamide — LSD redirects here. For other uses, see LSD (disambiguation). LSD 25 redirects here. For the dock landing ship, see USS San Marcos (LSD 25). For the Fringe episode, see Lysergic Acid Diethylamide (Fringe). Lysergic acid diethylamide … Wikipedia
Recreational drug use — is the use of a drug, usually psychoactive, with the intention of creating or enhancing recreational experience. Such use is controversial, however, often being considered to be also drug abuse, and it is often illegal. Also, it may overlap with… … Wikipedia