- Alois Alzheimer
Infobox Medical Person
Aloysius Alzheimer =Aloysius Alzheimer
caption =The plaque for Alois Alzheimer in Wrocław
birth_date =birth date|1864|6|14|mf=y
death_date =death date and age|1915|12|19|1864|6|14|mf=y
known_for =First published case of "presenile
dementia" ( Alzheimer's disease)
University of Tübingen University of Würzburg
work_institutions =City Mental Asylum,
Frankfurt am Main
Aloysius "Alois" Alzheimer (14 June 1864 - 19 December 1915) was a German
psychiatristand neuropathologistand a colleague of Emil Kraepelin. Alzheimer is credited with the first published case of "presenile dementia", which Kraepelin would later identify as Alzheimer's disease.
Alzheimer was born in
His father served in the office of notary public in the family's hometown. [ [http://www.marktbreit.de/kultur_bildung/alzheimer_engl.htm "Marktbreit: Alzheimer´s Birthplace"] ] Alzheimer attended
Aschaffenburg, Tübingen, Berlin, and Würzburg universities. He received a medical degree at Würzburg University in 1887. In the following year, he spent five months assisting mentally ill women, before he took an office in the city mental asylum in Frankfurt am Main: the Städtische Anstalt für Irre und Epileptische (Asylum for lunatics and epileptics). Emil Sioliwas the dean of that asylum (1852-1922). Another neurologist, Franz Nissl(1860-1919), began to work in that same asylum with Alzheimer, and they knew each other. Much of Alzheimer's later work on brain pathology made use of Nissl's method of silver staining of the histologicalsections. Alzheimer was the co-founder and co-publisher of the journal "Zeitschrift für die gesamte Neurologie und Psychiatrie". He never wrote a book that he could call his own. In 1901, Alzheimer observed a patient at the Frankfurt Asylum named Mrs. Auguste Deter. The 51-year-old patient had strange behavioral symptoms, including a loss of short-term memory. This patient would become his obsession over the coming years. In April 1906, Mrs. D. died and Alzheimer had the patient records and the brain sent to Munich where he was working at Kraepelin's lab. Together with two Italian physicians, he would use the staining techniques to identify amyloidplaques and
Since German was the common language of science and especially of Psychology of the time, Kraepelin's use of Alzheimer's disease in a textbook would make the name famous. By 1911, the disease was being used by European physicians to diagnose patients in the US.
In mid-December 1915, Alzheimer fell ill on the train on the way to the University of Breslau, where he had been appointed professor of psychiatry in 1912. Most probably he had a
streptococcalinfection and subsequent rheumatic feverand kidney failure. He died of heart failureat the age of 51 in Breslau(now Wrocław, Poland).
* [http://www.whonamedit.com/doctor.cfm/177.html/ Who Named It? - Alois Alzheimer]
* [http://www.alzheimers-research.org.uk/news/article.php?type=News&archive=1&id=71 Alzheimer's: 100 years on]
* [http://www.ibro.info/Pub/Pub_Main_Display.asp?LC_Docs_ID=3445 Alois Alzheimer's Biography, International Brain Research Organization]
* [http://www.med.uni-muenchen.de/haass Ludwig-Maximilians-University Munich, Laboratory for Neurodegenerative Disease Research - Prof. Dr. Christian Haass]
* [http://www.yorku.ca/ahp/?p=30 Bibliography of secondary sources] on Alois Alzheimer and Alzheimer's disease, selected from peer-reviewed journals.
* Graeber Manuel B. [http://www.ibro.info/media/pdf/si-his-pdf-pdf9.pdf "Alois Alzheimer (1864-1915)"]
International Brain Research Organization
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