DENND4A

DENN/MADD domain containing 4A
Identifiers
Symbols	DENND4A; FLJ33949; IRLB; KIAA0476; MYCPBP
External IDs	OMIM: 600382 HomoloGene: 55933 GeneCards: DENND4A Gene
Gene Ontology Molecular function • DNA binding • protein binding Cellular component • nucleus Biological process • regulation of transcription, DNA-dependent Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	10260	102442
Ensembl	ENSG00000174485	ENSMUSG00000053641
UniProt	Q7Z401	n/a
RefSeq (mRNA)	NM_001144823.1	NM_001162917.1
RefSeq (protein)	NP_001138295.1	NP_001156389.1
Location (UCSC)	Chr 15: 65.95 – 66.08 Mb	Chr 9: 64.66 – 64.77 Mb
PubMed search	[1]	[2]

C-myc promoter-binding protein is a protein that in humans is encoded by the DENND4A gene.^[1][2][3]

References

1. ^ Stasiv YZ, Mashkova TD, Chernov BK, Sokolova IV, Itkes AV, Kisselev LL (Sep 1994). "Cloning of a cDNA encoding a human protein which binds a sequence in the c-myc gene similar to the interferon-stimulated response element". Gene 145 (2): 267–72. doi:10.1016/0378-1119(94)90018-3. PMID 8056341. 
2. ^ Semova N, Kapanadze B, Corcoran M, Kutsenko A, Baranova A, Semov A (Aug 2003). "Molecular cloning, structural analysis, and expression of a human IRLB, MYC promoter-binding protein: new DENN domain-containing protein family emerges small star, filled". Genomics 82 (3): 343–54. doi:10.1016/S0888-7543(03)00103-4. PMID 12906859. 
3. ^ "Entrez Gene: DENND4A DENN/MADD domain containing 4A". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10260. 

Further reading

• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1847948. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.". Curr. Biol. 14 (16): 1436–50. doi:10.1016/j.cub.2004.07.051. PMID 15324660. 
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Uramoto H, Izumi H, Ise T, et al. (2002). "p73 Interacts with c-Myc to regulate Y-box-binding protein-1 expression.". J. Biol. Chem. 277 (35): 31694–702. doi:10.1074/jbc.M200266200. PMID 12080043.