Depigmentation

Depigmentation

Depigmentation is the lightening of the skin, or loss of pigment. Depigmentation of the skin can be caused by a number of local and systemic conditions. The pigment loss can be partial (injury to the skin) or complete (caused by vitiligo). It can be temporary (from tinea versicolor) or permanent (from albinism).

Most commonly, depigmentation of the skin is linked to people born with vitiligo,which produces differing areas of light and dark skin. These individuals, if they so decided to use a lightening process to even out their skin tone, could apply a topical cream containing the organic compound monobenzone to lessen the remaining pigment. The brand drug incorporating 20% monobenzone is Benoquin, made by ICN.

Increasingly, people who are not afflicted with the vitiligo experiment with lower concentrations of monobenzone creams in the hope of lightening their skin tone evenly. An alternate method of lightening is to use the chemical mequinol over an extended period of time. Both monobenzone and mequinol produce dramatic skin whitening, but react very differently. Mequinol leaves the skin looking extremely pale. However, tanning is still possible. Monobenzone applied topically completely removes pigment in the long term and vigorous sun-safety must to be adhered to for life to avoid severe sun burn and melanomas. People using monobenzone without previously having vitiligo do so because standard products containing hydroquinone or other lightening agents are not effective for their skin and due to price and active ingredient strength. However, monobenzone is not recommended for skin conditions other than vitiligo. AP reports that both hydroquinone and Benoquin were found in the home of popstar Michael Jackson.[1]

For stubborn pigmented lesions the Q-switched ruby laser, cryotherapy or TCA peels can be used to ensure the skin remains pigment-free.

References


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Look at other dictionaries:

  • dépigmentation — [ depigmɑ̃tasjɔ̃ ] n. f. • 1873; de dé et pigment ♦ Biol., méd. Perte ou suppression du pigment (1o) d un tissu, notamment de la peau. Dépigmentation totale. ⇒ albinisme. ● dépigmentation nom féminin Décoloration de la peau provoquée par une… …   Encyclopédie Universelle

  • depigmentation — [dē΄pig mən tā′shən] n. loss of, or deficiency in, pigmentation …   English World dictionary

  • depigmentation — noun Date: 1889 loss of normal pigmentation …   New Collegiate Dictionary

  • depigmentation — /dee pig meuhn tay sheuhn/, n. Pathol. loss of pigment. [1885 90; DE + PIGMENTATION] * * * …   Universalium

  • depigmentation — noun The loss of the skins normal pigmentation …   Wiktionary

  • Depigmentation — Loss of color (pigment) from the skin, mucous membranes, hair, or retina of the eye. The color of the skin, mucous membranes, hair, and retina is due to the deposition of melanin, which is a coloring matter. Melanin is produced by specialized… …   Medical dictionary

  • Depigmentation — De|pig|men|ta|ti|on die; , en <zu ↑de... u. ↑Pigmentation> die Verringerung der Anzahl der Pigmentkörperchen in Haut, Haaren u. Augen während der ↑phylogenetischen Entwicklung des Menschen; vgl. ↑...ation/...ierung …   Das große Fremdwörterbuch

  • depigmentation — n. loss of pigment …   English contemporary dictionary

  • depigmentation — de·pigmentation …   English syllables

  • depigmentation — de•pig•men•ta•tion [[t]diˌpɪg mənˈteɪ ʃən[/t]] n. pat loss of pigment …   From formal English to slang

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