mir-156 microRNA precursor

mir-156 microRNA precursor
Predicted secondary structure and sequence conservation of mir-156
Identifiers
Symbol	mir-156
Rfam	RF00073
miRBase	MI0000178
miRBase family	MIPF0000008
Other data
RNA type	Gene; miRNA
Domain(s)	Eukaryota
GO	0035195 0035068
SO	0001244

MicroRNA (miRNA) precursor mir-156 is a family of plant non-coding RNA. This microRNA has now been predicted or experimentally confirmed in a range of plant species (MIPF0000008). Animal miRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. In plants the precursor sequences may be longer, and the carpel factory (caf) enzyme appears to be involved in processing. In this case the mature sequence comes from the 5' arm of the precursor, and both Arabidopsis thaliana and rice genomes contain a number of related miRNA precursors which give rise to almost identical mature sequences. The extents of the hairpin precursors are not generally known and are estimated based on hairpin prediction. The products are thought to have regulatory roles through complementarity to mRNA.

Further reading

• Reinhart, BJ; Weinstein EG, Rhoades MW, Bartel B, Bartel DP (2002). "MicroRNAs in plants". Genes Dev 16 (13): 1616–1626. doi:10.1101/gad.1004402. PMC 186362. PMID 12101121. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=186362. 
• Ambros, V (2001). "microRNAs: tiny regulators with great potential". Cell 107 (7): 823–826. doi:10.1016/S0092-8674(01)00616-X. PMID 11779458. 
• Zhang B, Pan X (July 2009). "Expression of microRNAs in cotton". Mol. Biotechnol. 42 (3): 269–74. doi:10.1007/s12033-009-9163-y. PMID 19288227. 

External links

• Rfam page for mir-156 microRNA precursor
• MIPF0000008