Cichoric acid

Cichoric acid
Cichoric acid
Identifiers
CAS number 6537-80-0 YesY
PubChem 5281764
KEGG C10437 YesY
ChEMBL CHEMBL282731 N
Jmol-3D images Image 1
Properties
Molecular formula C22H18O12
Molar mass 474.371 g/mol
 N acid (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Cichoric acid is a hydroxycinnamic acid, an organic compound of the phenylpropanoid class and occurs in a variety of plant species. It is a derivative of both caffeic acid and tartaric acid.[1] As a suitable marker for the distinction of Echinacea species, it is often assayed using RP-HPLC and Thin layer chromatography (TLC) methods.[2] It has the chemical formula C22H18O12.

Sources

Cichoric acid has first been isolated from Cichorium intybus (chicory) but also occurs in significant amounts in Echinacea, particularly E. purpurea, dandelion leaves, basil, lemon balm and in aquatic plants, including algae and sea grasses.[3][4]

Biological functions

Cichoric acid has been shown to stimulate phagocytosis in both in vitro and in vivo studies, to inhibit the function of hyaluronidase (an enzyme which breaks down hyaluronic acid in the human body), protect collagen from damage due to free radicals, and inhibit the function of HIV-1 integrase.[5][6]

References

  1. ^ Hall III, Clifford; Jurgen G. Schwarz (2002) John Shi, G. Mazza, Marc Le Maguer ed. Functional Foods: Biochemical & Processing Aspects 2 CRC Press p. 241 ISBN 1566769027 http://books.google.com/?id=rEr8g-phGHAC. Retrieved 2008-12-09 
  2. ^ Bauer R, Khan IA, Wagner H. Echinacea-Drogen, Standardisierung mittels HPLC und DC. Deutsche Apotheker Zeitung, 1986, 126:1065–1070. Citation in WHO Monographs on Selected Medicinal Plants - Volume 1
  3. ^ I.D. Chkhikvishvili and G.I. Kahrebava (2001). “Cichoric and Chlorogenic Acids in Plant Species from Georgia”. Applied Biochemistry and Microbiology, 37 (2): 188-191. doi: 10.1023/a:1002888016985
  4. ^ Jungmin Lee (2010). Short communication “Caffeic acid derivatives in dried Lamiaceae and Echinacea purpurea products”. Journal of Functional Foods 2, 158-162. doi:10.1016/j.jff.2010.02.003
  5. ^ Mazza, G.; Oomah, B. Dave (2000), Herbs, Botanicals & Teas, CRC Press, pp. 51, ISBN 1566768519, http://books.google.com/?id=Au1HLD7eyZQC, retrieved 2008-12-09 
  6. ^ Miller, Sandra Carol; Yu, He-Ci (2004), Echinacea, CRC Press, pp. 140, ISBN 0415288282, http://books.google.com/?id=WMGlDuGhKq8, retrieved 2008-12-09 

Wikimedia Foundation. 2010.

Игры ⚽ Нужно сделать НИР?

Look at other dictionaries:

  • Hydroxycinnamic acid — Hydroxycinnamic acids are a class of polyphenols having a C6 C3 skeleton. These compounds are hydroxy derivatives of cinnamic acid. In the category of phytochemicals that can be found in food, there are : Alpha cyano 4 hydroxycinnamic acid… …   Wikipedia

  • Tartaric acid — Tartaric acid[1] …   Wikipedia

  • Chlorogenic acid — IUPAC name (1S,3R,4R,5R) 3 {[(2Z) 3 (3,4 dihydr …   Wikipedia

  • Ferulic acid — IUPAC name (E) 3 (4 hydroxy 3 methoxy phenyl)prop 2 enoic acid …   Wikipedia

  • Cinnamic acid — Cinnamic acid …   Wikipedia

  • Coumaric acid — p Coumaric acid …   Wikipedia

  • Coutaric acid — IUPAC name (2R,3R) 2 Hydroxy 3 (((E) 3 (4 hydroxyphenyl)acryloyl)oxy)succi …   Wikipedia

  • Diferulic acids — (also known as dehydrodiferulic acids) are organic compounds that have the general chemical formula C20H18O8, they are formed by dimerisation of ferulic acid. Just as ferulic acid is not the proper IUPAC name, the diferulic acids also tend to… …   Wikipedia

  • Cynarine — IUPAC name …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”