(isocitrate dehydrogenase (NADP+)) kinase

(isocitrate dehydrogenase (NADP+)) kinase

In enzymology, a [isocitrate dehydrogenase (NADP+)] kinase (EC number|2.7.11.5) is an enzyme that catalyzes the chemical reaction::ATP + [isocitrate dehydrogenase (NADP+)] ightleftharpoons ADP + [isocitrate dehydrogenase (NADP+)] phosphate

Thus, the two substrates of this enzyme are ATP and [isocitrate dehydrogenase (NADP+)] , whereas its two products are ADP and [isocitrate dehydrogenase (NADP+) phosphate] .

This enzyme belongs to the family of transferases, specifically those transferring a phosphate group to the sidechain oxygen atom of serine or threonine residues in proteins (protein-serine/threonine kinases).

The CAS registry number for this enzyme class is CAS registry|83682-93-3.

Other names

The systematic name of this enzyme class is ATP: [isocitrate dehydrogenase (NADP+)] phosphotransferase. Other names in common use include [isocitrate dehydrogenase (NADP+)] kinase, ICDH kinase/phosphatase, IDH kinase, IDH kinase/phosphatase, IDH-K/P, IDHK/P, isocitrate dehydrogenase kinase (phosphorylating), isocitrate dehydrogenase kinase/phosphatase, and STK3. This enzyme participates in mapk signaling pathway.

References

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External links

Gene Ontology (GO) codes


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