Inositol phosphate

Inositol phosphate
Inositol
Phosphate group

Inositol phosphates are a group of mono- to polyphosphorylated inositols. They play crucial roles in diverse cellular functions, such as cell growth, apoptosis, cell migration, endocytosis, and cell differentiation. The group comprises:

Contents

Functions

Inositol triphosphate

Main article: Inositol triphosphate

Inositol trisphosphates act on the inositol triphosphate receptor to release calcium into the cytoplasm. Further reading: Function of calcium in humans

Other

Inositol tetra-, penta-, and hexa-phosphates have been implicated in gene expression[1] and Steger[2] (both in Science Magazine).

References

  1. ^ Shen, X; Xiao, H; Ranallo, R; Wu, WH; Wu, C (2003). "Modulation of ATP-dependent chromatin-remodeling complexes by inositol polyphosphates". Science 299 (5603): 112–4. doi:10.1126/science.1078068. PMID 12434013. 
  2. ^ Steger, DJ; Haswell, ES; Miller, AL; Wente, SR; O'Shea, EK (2003). "Regulation of chromatin remodeling by inositol polyphosphates". Science 299 (5603): 114–6. doi:10.1126/science.1078062. PMC 1458531. PMID 12434012. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1458531. 

External links

v · Lipids: phospholipids
Glycerol backbone
(Glycerophospholipids/
Phosphoglycerides)
Sphingosine backbone
Metabolites

M: MET

mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m

k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon

m(A16/C10),i(k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)
biochemical families: prot · nucl · carb (glpr, alco, glys) · lipd (fata/i, phld, strd, gllp, eico) · amac/i · ncbs/i · ttpy/i



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Look at other dictionaries:

  • Inositol-phosphate phosphatase — In enzymology, an inositol phosphate phosphatase (EC number|3.1.3.25) is an enzyme that catalyzes the chemical reaction:myo inositol phosphate + H2O ightleftharpoons myo inositol + phosphateThus, the two substrates of this enzyme are myo inositol …   Wikipedia

  • inositol-phosphate phosphatase — ino·si·tol phos·phate phos·pha·tase (in oґsĭ tol fosґfāt fosґfə tās) [EC 3.1.3.25] an enzyme of the hydrolase class that catalyzes the dephosphorylation of myo inositol phosphate to form myo inositol, acting on five of the six …   Medical dictionary

  • Inositol monophosphatase — Inositol monophosphatase, commonly referred to as IMPase, is an enzyme found in all cells and is thought to be key in bipolar disorder (manic depression).The enzyme itself is a dimer comprising 277 amino acid residues per subunit which… …   Wikipedia

  • Inositol pentakisphosphate — (abbreviated IP5) is a molecule derived from Inositol tetrakisphosphate by adding a phosphate group with the help of the Inositol polyphosphate multikinase (IPMK). It is believed to be one of the many second messengers in the inositol phosphate… …   Wikipedia

  • Inositol — myo Inositol[1] …   Wikipedia

  • Inositol-3-phosphate synthase — In enzymology, an inositol 3 phosphate synthase (EC number|5.5.1.4) is an enzyme that catalyzes the chemical reaction:D glucose 6 phosphate ightleftharpoons 1D myo inositol 3 phosphateHence, this enzyme has one substrate, D glucose 6 phosphate,… …   Wikipedia

  • Inositol-1,4-bisphosphate 1-phosphatase — In enzymology, an inositol 1,4 bisphosphate 1 phosphatase (EC number|3.1.3.57) is an enzyme that catalyzes the chemical reaction:1D myo inositol 1,4 bisphosphate + H2O ightleftharpoons 1D myo inositol 4 phosphate + phosphateThus, the two… …   Wikipedia

  • Inositol 3-kinase — In enzymology, an inositol 3 kinase (EC number|2.7.1.64) is an enzyme that catalyzes the chemical reaction:ATP + myo inositol ightleftharpoons ADP + 1D myo inositol 3 phosphateThus, the two substrates of this enzyme are ATP and myo inositol,… …   Wikipedia

  • Inositol-tetrakisphosphate 1-kinase — In enzymology, an inositol tetrakisphosphate 1 kinase (EC number|2.7.1.134) is an enzyme that catalyzes the chemical reaction:ATP + 1D myo inositol 3,4,5,6 tetrakisphosphate ightleftharpoons ADP + 1D myo inositol 1,3,4,5,6 pentakisphosphateThus,… …   Wikipedia

  • Inositol triphosphate receptor — protein Name = inositol 1,4,5 triphosphate receptor, type 1 caption = width = HGNCid = 6180 Symbol = ITPR1 AltSymbols = EntrezGene = 3708 OMIM = 147265 RefSeq = NM 002222 UniProt = Q14643 PDB = ECnumber = Chromosome = 3 Arm = p Band = 26.1… …   Wikipedia

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