Ablative brain surgery

Ablative brain surgery

Ablative surgery is the surgical ablation by burning or freezing of brain tissue to treat neurological or psychological disorders. The lesions it causes are irreversible.

Uses

Parkinson's disease

Surgical ablation has been used to treat Parkinson's disease. In the 1990s, the pallidum was a common surgical target. Unilateral pallidotomy improves tremor and dyskinesia on one side of the body (opposite the side of the brain surgery), but bilateral pallidotomy was found to cause irreversible deterioration in speech and cognition. The thalamus is another potential target for treating tremor; in some countries, so is the subthalamic nucleus, although not in the United States due to its severe side effects. Generally, deep brain stimulation surgery (DBS) is considered preferable to ablation because it has the same effect and is adjustable and reversible.cite web |url= http://www.waparkinsons.org/edu_research/articles/Stereotactic_Surgery.html |title= Stereotactic Surgery |publisher= American Parkinson Disease Association |last= Samii|first= Ali |date= 2002 |accessdate= 2008-05-01 ] However, for patients for whom DBS is not feasible, ablation of the subthalamic nucleus has been shown to be safe and effective. [cite web |title= Unilateral Ablative Lesions of the Subthalamic Nucleus in Advanced Parkinson Disease: Long-term Follow-up |url= http://www.assfn.org/meetings/neuro.pdf |publisher= American Society for Stereotactic and Functional Neurosurgery |format= PDF |author= O. Barlas |coauthors= H. Hanagasi; M. Emre |accessdate= 2008-05-01 ]

Cluster headaches

Cluster headaches have been treated by ablation of the trigeminal nerve, but have not been very effective. Other surgical treatments for cluster headaches are under investigation.cite web |format= PDF |title= Stereotactic and Functional Neurosurgery News |url= http://www.assfn.org/society/Fall07newsletter.pdf |publisher= American Association of Neurological Surgeons |date= Fall 2007 |accessdate= 2008-05-01 ]

Psychiatric disorders

In the People's Republic of China, surgical ablation was used to treat psychological and neurological disorders, particularly schizophrenia, but also including clinical depression, obsessive-compulsive disorder, and epilepsy.cite news |last= Zamiska |first= Nicholas |title= In China, Brain Surgery Is Pushed on the Mentally Ill |publisher= "The Wall Street Journal" |date =November 2, 2007 |accessdate= 2008-05-01] The official Xinhua News Agency has since reported that China's Ministry of Health has banned the procedure for schizophrenia and severely restricted the practice for other conditions.cite news |last= Zamiska |first= Nicholas |title= China Bans Irreversible Brain Procedure |publisher= "The Wall Street Journal" |date= April 28, 2008 |accessdate= 2008-05-01]

Methods

Lasers have been shown to be effective in ablation of both cerebral and cerebellar tissue. A laser called , for example, allows great precision in location and size of the lesion and causes little to no thermal damage to adjacent tissue. [cite journal |title= Er:YAG Laser Ablation of Cerebellar and Cerebral Tissue |last= Gülsoy |first= M. |coauthors= "et al." |journal= Lasers in Medical Science |volume= 16 |issue= 1 |date= 2001 |url= http://www.springerlink.com/content/61pnkwcdr0vwwfdb/ |accessdate= 2008-05-01 ]

References


Wikimedia Foundation. 2010.

См. также в других словарях:

  • Endometriosis — Classification and external resources ICD 10 N80 I …   Wikipedia

  • High-intensity focused ultrasound — Contents 1 Theory 2 Aiming 3 How HIFU works 4 Method of use …   Wikipedia

  • Neurosurgery — Occupation Activity sectors Surgery Description Education required Doctor of Medicine, Doctor of Osteopathic Med …   Wikipedia

  • Radiosurgery — This article is about the medical procedure. For the album by American rock band New Found Glory, see Radiosurgery (album). Radiosurgery Intervention CLINAC: a model of steerable linear accelerator commonly used in radiosurgery …   Wikipedia

  • Ablation — is defined as the removal of material from the surface of an object by vaporization, chipping, or other erosive processes. The term occurs in space physics associated with atmospheric reentry, in glaciology, medicine and passive fire… …   Wikipedia

  • Gamma knife — Gamma Knife® (or Leksell Gamma Knife®) is a device used to treat brain tumors with a high dose of radiation therapy in one day. The device was invented by Lars Leksell, a Swedish neurosurgeon, in 1967 at the Karolinska Institute in Sweden. Gamma… …   Wikipedia

  • Hyperthyroidism — Classification and external resources Triiodothyronine (T3, pictured) and thyroxine (T4) are both forms of thyroid hormone. ICD 10 …   Wikipedia

  • Scramjet — Part of a series on Aircraft propulsion Shaft engines (to drive pr …   Wikipedia

  • Management of prostate cancer — Treatment for prostate cancer may involve active surveillance, surgery, radiation therapy including brachytherapy (prostate brachytherapy) and external beam radiation therapy, High intensity focused ultrasound (HIFU), chemotherapy, cryosurgery,… …   Wikipedia

  • Management of cancer — This article needs more medical references for verification. Please review the contents of the article and add the appropriate references if you can. Help may also be requested at Wikipedia:WikiProject Medicine. Please remove this message after… …   Wikipedia


Поделиться ссылкой на выделенное

Прямая ссылка:
Нажмите правой клавишей мыши и выберите «Копировать ссылку»