AIDS defining clinical condition


AIDS defining clinical condition

AIDS defining clinical conditions is the terminology given to a list of diseases published by the United States government run Centers for Disease Control and Prevention (CDC). This list governs the U.S. government classification of HIV disease. This is to allow the government to handle epidemic statistics and define who receives US government assistance. In 1993, the CDC added pulmonary tuberculosis, recurrent pneumonia, and invasive cervical cancer to the list of clinical conditions in the AIDS surveillance case definition published in 1987 and expanded the AIDS surveillance case definition to include all HIV-infected persons with CD4+ T-lymphocyte counts of less than 200 cells/uL or a CD4+ percentage of less than 14. Considerable variation exists in the relative risk of death following different AIDS defining clinical conditions.

According to the US CDC definition, you have AIDS if you are infected with HIV and present with one of the following:

A CD4+ T-cell count below 200 cells/µl (or a CD4+ T-cell percentage of total lymphocytes of less than 14%)

or

you have one of the following defining illnesses:

*Candidiasis of bronchi, trachea, or lungs
*Candidiasis esophageal
*Cervical cancer (invasive)
*Coccidioidomycosis, disseminated or extrapulmonary
*Cryptococcosis, extrapulmonary
*Cryptosporidiosis, chronic intestinal for longer than 1 month
*Cytomegalovirus disease (other than liver, spleen or lymph nodes
*Encephalopathy (HIV-related)
*Herpes simplex: chronic ulcer(s) (for more than 1 month); or bronchitis, pneumonitis, or esophagitis
*Histoplasmosis, disseminated or extrapulmonary
*Isosporiasis, chronic intestinal (for more than 1 month)
*Kaposi's sarcoma
*Lymphoma Burkitt's, immunoblastic or primary brain
*Mycobacterium avium complex
*Mycobacterium, other species, disseminated or extrapulmonary
*Pneumocystis jiroveci pneumonia (formerly Pneumocystis carinii)
*Pneumonia (recurrent)
*Progressive multifocal leukoencephalopathy
*Salmonella septicemia (recurrent)
*Toxoplasmosis of the brain
*Tuberculosis
*Wasting syndrome due to HIV

People who are not infected with HIV may also develop these conditions; this does not mean they have AIDS. However, when an individual presents laboratory evidence against HIV infection, a diagnosis of AIDS is ruled out unless the patient has not:

undergone high-dose corticoid therapy or other immunosuppressive/cytotoxic therapy in the three months before the onset of the indicator disease OR been diagnosed with Hodgkin's disease, non-Hodgkin's lymphoma, lymphocytic leukemia, multiple myeloma, or any cancer of lymphoreticular or histiocytic tissue, or angioimmunoblastic lymphoadenopathy OR a genetic immunodeficiency syndrome atypical of HIV infection, such as one involving hypogamma globulinemia

AND

the individual has had "Pneumocystis jiroveci" pneumonia OR one of the above defining illnesses AND a CD4+ T-cell count below 200 cells/µl (or a CD4+ T-cell percentage of total lymphocytes of less than 14%).

References

*CDC. Revision of the CDC surveillance case definition for acquired immunodeficiency syndrome. MMWR 1987;36:1-15S.
*CDC. [http://www.cdc.gov/mmwr/preview/mmwrhtml/00018871.htm 1993 Revised Classification System for HIV Infection and Expanded Surveillance Case Definition for AIDS Among Adolescents and Adults]
* [http://aidsinfo.nih.gov/other/cbrochure/english/01_en.html AIDS info]
* [http://www.aidsonline.com/pt/re/aids/abstract.00002030-199809000-00006.htm Disease progression and survival following specific AIDS-defining conditions: a retrospective cohort study of 2048 HIV-infected persons in London.]


Wikimedia Foundation. 2010.

Look at other dictionaries:

  • AIDS — For other uses, see AIDS (disambiguation). Acquired immunodeficiency syndrome (AIDS) Classification and external resources …   Wikipedia

  • AIDS Clinical Trials Group — The AIDS Clinical Trials Group (ACTG) is the largest HIV clinical trials organization in the world, playing a major role in setting standards of care for HIV infection and opportunistic diseases related to HIV and AIDS in the United States and… …   Wikipedia

  • Misconceptions about HIV and AIDS — The spread of HIV and AIDS has affected millions of people worldwide; AIDS is considered a pandemic.[1] In 2009, the World Health Organization (WHO) estimated that there are 33.4 million people worldwide living with HIV/AIDS, with… …   Wikipedia

  • Multicenter AIDS Cohort Study — The Multicenter AIDS Cohort Study (MACS) is an ongoing clinical study involving over 6,000 men infected with HIV. The study, a program of the Division of Acquired Immunodeficiency Syndrome, has been ongoing for over 25 years and has resulted in… …   Wikipedia

  • Origin of AIDS — False color scanning electron micrograph of HIV 1, in green, budding from cultured lymphocyte. AIDS is caused by the Human immunodeficiency virus (HIV), which originated in non human primates in Sub Saharan Africa and was transferred to humans… …   Wikipedia

  • NAMES Project AIDS Memorial Quilt — The AIDS Quilt The NAMES Project AIDS Memorial Quilt, often abbreviated to AIDS Memorial Quilt, is an enormous quilt made as a memorial to and celebration of the lives of people who have died of AIDS related causes. Weighing an estimated 54 tons …   Wikipedia

  • People With AIDS — The People With AIDS (PWA) Self Empowerment Movement is a social movement by those diagnosed with HIV/AIDS which grew out of San Francisco in the early 1980s. The PWA Self Empowerment Movement believes that those diagnosed as having AIDS should… …   Wikipedia

  • OPV AIDS hypothesis — Main articles: AIDS origin and AIDS origins opposed to scientific consensus The oral polio vaccine (OPV) AIDS hypothesis argues that the AIDS pandemic originated from live polio vaccines prepared in chimpanzee tissue cultures and then… …   Wikipedia

  • Discredited AIDS origins theories — This article contains hypotheses not supported by scientific evidence. For current scientifically based hypotheses, see Origin of AIDS. Various conspiracy theories and other such hypotheses have arisen to speculate about the origins of HIV and… …   Wikipedia

  • National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention — The National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP) is a part of the Centers for Disease Control and Prevention and is responsible for public health surveillance, prevention research, and programs to prevent and… …   Wikipedia


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.