Super AIDS

Super AIDS

"Super AIDS" is an informal term used by some sourcesFact|date=May 2008 for a strain of the human immunodeficiency virus that arose in New York City in 2005.cite journal |author= |title=Investigation of a new diagnosis of multidrug-resistant, dual-tropic HIV-1 infection--New York City, 2005 |journal=Morbidity and Mortality Weekly Report|volume=55 |issue=29 |pages=793–6 |year=2006 |month=July |pmid=16874293 |doi= |url=] cite journal |author=Blick G, Kagan RM, Coakley E, "et al" |title=The probable source of both the primary multidrug-resistant (MDR) HIV-1 strain found in a patient with rapid progression to AIDS and a second recombinant MDR strain found in a chronically HIV-1-infected patient |journal=J. Infect. Dis. |volume=195 |issue=9 |pages=1250–9 |year=2007 |month=May |pmid=17396993 |doi=10.1086/512240 |url= ] cite journal |author=Markowitz M, Mohri H, Mehandru S, "et al" |title=Infection with multidrug resistant, dual-tropic HIV-1 and rapid progression to AIDS: a case report |journal=Lancet |volume=365 |issue=9464 |pages=1031–8 |year=2005 |pmid=15781098 |doi=10.1016/S0140-6736(05)71139-9 |url=]

The phrase "Super AIDS" is not used in formal contexts, but it was used in the South Park episode The Death of Eric Cartman.cite web |url= |title=South Park: The Death of Eric Cartman - |format= |work= |accessdate=] cite web |url= |title=Super-AIDS - Clips - South Park Studios |format= |work= |accessdate=]

HIV infection

Typically, the "wild" type of HIV (the strain of HIV found in individuals not treated with Antiretroviral drugs) is much more effective at attacking the human immune system than the types that evolve in the presence of antiretroviral drugs. Thus, by changing the selection pressure (from being infection driven to being drug-avoidance driven) retroviral drug treatment causes HIV to evolve to a more innocuous form, less efficient at infecting T-cells.

Super AIDS, however, was a strain that was not only resistant to anti-retroviral drugs, but it was more effective than "wild" HIV at infecting T-cells.

The strain retained vulnerability to enfuvirtide.cite web |url= | U.S. |format= |work= |accessdate=]


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