In cell biology, a phagosome is a vacuole formed around a particle absorbed by phagocytosis. The vacuole is formed by the fusion of the cell membrane around the particle. A phagosome is a cellular compartment in which pathogenic microorganisms can be killed and digested. Phagosomes fuse with lysosomes in their maturation process, forming phagolysosomes. Some bacterial pathogens which enter cells inside phagosomes, actually reproduce either inside of the formed phagolysosome (Coxiella) [Hackstadt T and Williams J C "Biochemical stratagem for obligate parasitism of eukaryotic cells by Coxiella burnetii." Proc Natl Acad Sci U S A. 1981 May; 78(5): 3240–3244.] , or escape into the cytoplasm before the phagosome fuses with the lysosome (Rickettsia) [Winkler H H "Rickettsia Species (As Organisms)" Annual Review of Microbiology Vol. 44: 131-153 ] .


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  • phagosome — phagosome. См. фагосома. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Phagosome — Le phagosome est un organite formé dans une cellule phagocytaire à la suite de la phagocytose. On a d abord décrit la formation du phagosome comme étant une invagination de la membrane plasmique pour englober un corps étranger (bactérie ou débris …   Wikipédia en Français

  • phagosome — n. [Gr. phagein, to eat; soma, body] A membrane bound vesicle in the cytoplasm of a cell resulting from phagocytosis …   Dictionary of invertebrate zoology

  • phagosome — /fag euh sohm /, n. a vacuole within a phagocyte that contains bacteria or other ingested particles and that becomes fused with a lysosome. [1955 60; PHAGO + SOME3] * * * …   Universalium

  • phagosome — noun A membrane bound vacuole within a cell containing foreign material captured by phagocytosis. See Also: phagosomal …   Wiktionary

  • phagosome — A vesicle that forms around a particle (bacterial or other) within the phagocyte that engulfed it, separates from the cell membrane, and then fuses with and receives the contents of cytoplasmic granules (lysosomes), thus forming a phagolysosome… …   Medical dictionary

  • phagosome — phago·some …   English syllables

  • phagosome — phag•o•some [[t]ˈfæg əˌsoʊm[/t]] n. cbl a vacuole that contains the ingested matter of a phagocytic cell • Etymology: 1955–60 …   From formal English to slang

  • phagosome — ˈfagəˌsōm noun ( s) Etymology: phag + some (III) : a membrane bound vesicle that encloses particulate matter taken into the cell by phagocytosis …   Useful english dictionary

  • Phagosome crystal structures — Cells can ingest foreign particles by a process known as phagocytosis. If large numbers of small particles are introduced in this way, they arrange into crystallites.Cell assisted assembly of colloidal crystalliteSpatial confinement drives… …   Wikipedia

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