MS4A3

MS4A3

Membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific), also known as MS4A3, is a human gene.cite web | title = Entrez Gene: MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=932| accessdate = ]

PBB_Summary
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summary_text = This gene encodes a member of the membrane-spanning 4A gene family. Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member likely plays a role in signal transduction and may function as a subunit associated with receptor complexes. The gene encoding this protein is localized to 11q12, among a cluster of related family members. Alternative splicing may result in multiple transcript variants; however, not all variants have been fully described.cite web | title = Entrez Gene: MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=932| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Chinami M, Yano Y, Yang X, "et al." |title=Binding of HTm4 to cyclin-dependent kinase (Cdk)-associated phosphatase (KAP).Cdk2.cyclin A complex enhances the phosphatase activity of KAP, dissociates cyclin A, and facilitates KAP dephosphorylation of Cdk2. |journal=J. Biol. Chem. |volume=280 |issue= 17 |pages= 17235-42 |year= 2005 |pmid= 15671017 |doi= 10.1074/jbc.M413437200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Donato JL, Ko J, Kutok JL, "et al." |title=Human HTm4 is a hematopoietic cell cycle regulator. |journal=J. Clin. Invest. |volume=109 |issue= 1 |pages= 51-8 |year= 2002 |pmid= 11781350 |doi= 10.1172/JCI14025
*cite journal | author=Liang Y, Buckley TR, Tu L, "et al." |title=Structural organization of the human MS4A gene cluster on Chromosome 11q12. |journal=Immunogenetics |volume=53 |issue= 5 |pages= 357-68 |year= 2001 |pmid= 11486273 |doi=
*cite journal | author=Liang Y, Tedder TF |title=Identification of a CD20-, FcepsilonRIbeta-, and HTm4-related gene family: sixteen new MS4A family members expressed in human and mouse. |journal=Genomics |volume=72 |issue= 2 |pages= 119-27 |year= 2001 |pmid= 11401424 |doi= 10.1006/geno.2000.6472
*cite journal | author=Adra CN, Lelias JM, Kobayashi H, "et al." |title=Cloning of the cDNA for a hematopoietic cell-specific protein related to CD20 and the beta subunit of the high-affinity IgE receptor: evidence for a family of proteins with four membrane-spanning regions. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 21 |pages= 10178-82 |year= 1994 |pmid= 7524084 |doi=

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