Linsidomine

Drugbox
IUPAC_name = 3-Morpholin-4-yl-1-oxa-3-azonia-2-azanidacyclopent-3-en-5-imine


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ATC_prefix = C01
ATC_suffix = DX18
PubChem = 5219
DrugBank =
C=6|H=10|N=4|O=2
molecular_weight = 170.17 g/mol
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Linsidomine is a vasodilator.Linsidomine (SIN-1) is a metabolite of the antianginal drug molsidomine and acts by releasing NO from the endothelial cells nonenzymatically. It also hyperpolarizes the cell membrane through influencing the sodium-potassium pump and thereby rendering it less responsive to adrenergic stimulation ). Linsidomine injection at a dose of 1 mg produces usable erection in about 70% of patients and full erection in up to 50% of patients . Linsidomine does not appear to be associated with priapism .