Homoserine


Homoserine

Homoserine is an α-amino acid with the chemical formula HO2CCH(NH2)CH2CH2OH. L-Homoserine is not one of the common amino acids encoded by DNA. It differs from the proteinogenic amino acid serine by insertion of an additional methylene group. Homoserine, or its lactone form, is the product of a cyanogen bromide cleavage of a peptide by degradation of methionine.

Homoserine is an intermediate in the biosynthesis of three essential amino acids: methionine, threonine (an isomer] of homoserine), and isoleucine. It forms by two reductions of aspartic acid via the intermediacy of aspartate semialdehyde. [Berg, J. M.; Stryer, L. et al (2002), "Biochemistry". W.H. Freeman. ISBN 0-7167-4684-0]

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  • homoserine — homoserine. См. гомосерин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • homoserine — homoserinas statusas T sritis chemija formulė HOCH₂CH₂CH(NH₂)COOH atitikmenys: angl. homoserine rus. гомосерин ryšiai: sinonimas – 2 amino 4 hidroksibutano rūgštis …   Chemijos terminų aiškinamasis žodynas

  • homoserine — noun The amino acid 2 amino 4 hydroxybutanoic acid that is an intermediate in the biosynthesis of methionine, threonine and isoleucine …   Wiktionary

  • homoserine — Amino 4 hydroxybutyric acid; a hydroxyamino acid differing from serine in the possession of an additional CH2 group. An intermediate in the biosynthesis of cystathionine, threonine, and methionine. h. deaminase SYN: cystathionine γ lyase. h.… …   Medical dictionary

  • Homoserine lactone — Homosérine lactone Structure des acyl homosérine lactones Les Homosérine lactones sont des composés chimiques qui, sous forme acylée, sont impliqués dans le quorum sensing chez les bactéries. Différentes formes d acyl homosérine lactones sont… …   Wikipédia en Français

  • Homosérine Lactone — Structure des acyl homosérine lactones Les Homosérine lactones sont des composés chimiques qui, sous forme acylée, sont impliqués dans le quorum sensing chez les bactéries. Différentes formes d acyl homosérine lactones sont utilisées par diverses …   Wikipédia en Français

  • Homoserine lactone — Homoserine lactones are signaling chemicals involved in microbiological quorum sensing.They signal changes in gene expression, such as switching between the flagella gene and the gene for pili for the development of a biofilm.In the presence of… …   Wikipedia

  • Homoserine O-acetyltransferase — In enzymology, a homoserine O acetyltransferase (EC number|2.3.1.31) is an enzyme that catalyzes the chemical reaction:acetyl CoA + L homoserine ightleftharpoons CoA + O acetyl L homoserineThus, the two substrates of this enzyme are acetyl CoA… …   Wikipedia

  • Homoserine O-succinyltransferase — In enzymology, a homoserine O succinyltransferase (EC number|2.3.1.46) is an enzyme that catalyzes the chemical reaction:succinyl CoA + L homoserine ightleftharpoons CoA + O succinyl L homoserineThus, the two substrates of this enzyme are… …   Wikipedia

  • Homoserine kinase — In enzymology, a homoserine kinase (EC number|2.7.1.39) is an enzyme that catalyzes the chemical reaction:ATP + L homoserine ightleftharpoons ADP + O phospho L homoserineThus, the two substrates of this enzyme are ATP and L homoserine, whereas… …   Wikipedia