Nesprin


Nesprin

The Nesprins (nuclear envelope spectrin repeat[1]) are a family of proteins that are found primarily in the outer nuclear membrane. Nesprin-1 and -2 bind to the actin filaments.[citation needed] Nesprin-3 binds to plectin, which is bound to the intermediate filaments,[2] while nesprin-4 interacts with kinesin-1.[3]

See also

References

  1. ^ http://jcs.biologists.org/cgi/content/abstract/114/24/4485
  2. ^ Wilhelmsen, K; Litjens, SH; Kuikman, I; Tshimbalanga, N; Janssen, H; Van Den Bout, I; Raymond, K; Sonnenberg, A (Dec 2005). "Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectin" (Free full text). The Journal of cell biology 171 (5): 799–810. doi:10.1083/jcb.200506083. ISSN 0021-9525. PMC 2171291. PMID 16330710. http://www.jcb.org/cgi/pmidlookup?view=long&pmid=16330710. 
  3. ^ Roux, KJ; Crisp, ML; Liu, Q; Kim, D; Kozlov, S; Stewart, CL; Burke, B (Feb 2009). "Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization" (Free full text). Proceedings of the National Academy of Sciences of the United States of America 106 (7): 2194–9. doi:10.1073/pnas.0808602106. ISSN 0027-8424. PMC 2650131. PMID 19164528. http://www.pnas.org/cgi/pmidlookup?view=long&pmid=19164528.