CCNF

Cyclin F, also known as CCNF, is a human gene.cite web | title = Entrez Gene: CCNF cyclin F| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=899| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified.cite web | title = Entrez Gene: CCNF cyclin F| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=899| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Nehls M, Lüno K, Schorpp M, "et al." |title=YAC/P1 contigs defining the location of 56 microsatellite markers and several genes across a 3.4-cM interval on mouse chromosome 11. |journal=Mamm. Genome |volume=6 |issue= 5 |pages= 321–31 |year= 1995 |pmid= 7626882 |doi=
*cite journal | author=Bai C, Richman R, Elledge SJ |title=Human cyclin F. |journal=EMBO J. |volume=13 |issue= 24 |pages= 6087–98 |year= 1995 |pmid= 7813445 |doi=
*cite journal | author=Kraus B, Pohlschmidt M, Leung AL, "et al." |title=A novel cyclin gene (CCNF) in the region of the polycystic kidney disease gene (PKD1). |journal=Genomics |volume=24 |issue= 1 |pages= 27–33 |year= 1995 |pmid= 7896286 |doi= 10.1006/geno.1994.1578
*cite journal | author=Bai C, Sen P, Hofmann K, "et al." |title=SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box. |journal=Cell |volume=86 |issue= 2 |pages= 263–74 |year= 1996 |pmid= 8706131 |doi=
*cite journal | author=Kong M, Barnes EA, Ollendorff V, Donoghue DJ |title=Cyclin F regulates the nuclear localization of cyclin B1 through a cyclin-cyclin interaction. |journal=EMBO J. |volume=19 |issue= 6 |pages= 1378–88 |year= 2000 |pmid= 10716937 |doi= 10.1093/emboj/19.6.1378
*cite journal | author=Fung TK, Siu WY, Yam CH, "et al." |title=Cyclin F is degraded during G2-M by mechanisms fundamentally different from other cyclins. |journal=J. Biol. Chem. |volume=277 |issue= 38 |pages= 35140–9 |year= 2002 |pmid= 12122006 |doi= 10.1074/jbc.M205503200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406

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