GEMIN5


GEMIN5

Gem (nuclear organelle) associated protein 5, also known as GEMIN5, is a human gene.cite web | title = Entrez Gene: GEMIN5 gem (nuclear organelle) associated protein 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=25929| accessdate = ]

PBB_Summary
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summary_text = GEMIN5 is part of a large macromolecular complex localized to both the cytoplasm and the nucleus that plays a role in the cytoplasmic assembly of small nuclear ribonucleoproteins (snRNPs). Other members of this complex include SMN (MIM 600354), GEMIN2 (SIP1; MIM 602595), GEMIN3 (DDX20; MIM 606168), and GEMIN4 (MIM 606969). [supplied by OMIM] cite web | title = Entrez Gene: GEMIN5 gem (nuclear organelle) associated protein 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=25929| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Gubitz AK, Mourelatos Z, Abel L, "et al." |title=Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins. |journal=J. Biol. Chem. |volume=277 |issue= 7 |pages= 5631–6 |year= 2002 |pmid= 11714716 |doi= 10.1074/jbc.M109448200
*cite journal | author=Baccon J, Pellizzoni L, Rappsilber J, "et al." |title=Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex. |journal=J. Biol. Chem. |volume=277 |issue= 35 |pages= 31957–62 |year= 2002 |pmid= 12065586 |doi= 10.1074/jbc.M203478200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Battle DJ, Lau CK, Wan L, "et al." |title=The Gemin5 protein of the SMN complex identifies snRNAs. |journal=Mol. Cell |volume=23 |issue= 2 |pages= 273–9 |year= 2006 |pmid= 16857593 |doi= 10.1016/j.molcel.2006.05.036
*cite journal | author=Beausoleil SA, Villén J, Gerber SA, "et al." |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026
*cite journal | author=Kim EK, Noh KT, Yoon JH, "et al." |title=Positive regulation of ASK1-mediated c-Jun NH(2)-terminal kinase signaling pathway by the WD-repeat protein Gemin5. |journal=Cell Death Differ. |volume=14 |issue= 8 |pages= 1518–28 |year= 2007 |pmid= 17541429 |doi= 10.1038/sj.cdd.4402157
*cite journal | author=Hao le T, Fuller HR, Lam le T, "et al." |title=Absence of gemin5 from SMN complexes in nuclear Cajal bodies. |journal=BMC Cell Biol. |volume=8 |issue= |pages= 28 |year= 2007 |pmid= 17640370 |doi= 10.1186/1471-2121-8-28
*cite journal | author=Battle DJ, Kasim M, Wang J, Dreyfuss G |title=SMN-independent subunits of the SMN complex. Identification of a small nuclear ribonucleoprotein assembly intermediate. |journal=J. Biol. Chem. |volume=282 |issue= 38 |pages= 27953–9 |year= 2007 |pmid= 17640873 |doi= 10.1074/jbc.M702317200

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