Rho guanine nucleotide exchange factor (GEF) 5, also known as ARHGEF5, is a human gene.cite web | title = Entrez Gene: ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5| url =| accessdate = ]

section_title =
summary_text = Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization.cite web | title = Entrez Gene: ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5| url =| accessdate = ]


Further reading

citations =
*cite journal | author=Takai S, Chan AM, Yamada K, Miki T |title=Assignment of the human TIM proto-oncogene to 7q33-->q35. |journal=Cancer Genet. Cytogenet. |volume=83 |issue= 1 |pages= 87–9 |year= 1995 |pmid= 7656213 |doi=
*cite journal | author=Chan AM, McGovern ES, Catalano G, "et al." |title=Expression cDNA cloning of a novel oncogene with sequence similarity to regulators of small GTP-binding proteins. |journal=Oncogene |volume=9 |issue= 4 |pages= 1057–63 |year= 1994 |pmid= 8134109 |doi=
*cite journal | author=Snyder JT, Worthylake DK, Rossman KL, "et al." |title=Structural basis for the selective activation of Rho GTPases by Dbl exchange factors. |journal=Nat. Struct. Biol. |volume=9 |issue= 6 |pages= 468–75 |year= 2002 |pmid= 12006984 |doi= 10.1038/nsb796
*cite journal | author=Wistow G, Bernstein SL, Wyatt MK, "et al." |title=Expressed sequence tag analysis of adult human lens for the NEIBank Project: over 2000 non-redundant transcripts, novel genes and splice variants. |journal=Mol. Vis. |volume=8 |issue= |pages= 171–84 |year= 2002 |pmid= 12107413 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Hillier LW, Fulton RS, Fulton LA, "et al." |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Umetsu DT, Dekruyff RH |title=Regulation of tolerance in the respiratory tract: TIM-1, hygiene, and the environment. |journal=Ann. N. Y. Acad. Sci. |volume=1029 |issue= |pages= 88–93 |year= 2005 |pmid= 15681748 |doi= 10.1196/annals.1309.012
*cite journal | author=Benzinger A, Muster N, Koch HB, "et al." |title=Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer. |journal=Mol. Cell Proteomics |volume=4 |issue= 6 |pages= 785–95 |year= 2005 |pmid= 15778465 |doi= 10.1074/mcp.M500021-MCP200
*cite journal | author=Zhang Y, Wolf-Yadlin A, Ross PL, "et al." |title=Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules. |journal=Mol. Cell Proteomics |volume=4 |issue= 9 |pages= 1240–50 |year= 2005 |pmid= 15951569 |doi= 10.1074/mcp.M500089-MCP200

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