NCAPG


NCAPG
Non-SMC condensin I complex, subunit G
Identifiers
Symbols NCAPG; CAPG; CHCG; FLJ12450; HCAP-G; MGC126525; NY-MEL-3
External IDs OMIM606280 HomoloGene44071 GeneCards: NCAPG Gene
RNA expression pattern
PBB GE NCAPG 218662 s at tn.png
PBB GE NCAPG 218663 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 64151 n/a
Ensembl ENSG00000109805 n/a
UniProt Q9BPX3 n/a
RefSeq (mRNA) NM_022346 n/a
RefSeq (protein) NP_071741 n/a
Location (UCSC) Chr 4:
17.81 – 17.85 Mb
n/a
PubMed search [1] n/a

Condensin complex subunit 3 also known as condensin subunit CAP-G (CAP-G) or non-SMC condensin I complex subunit G (NCAPG) is a protein that in humans is encoded by the NCAPG gene.[1][2][3] CAP-G is a subunit of condensin I, a large protein complex involved in chromosome condensation.

Interactions

NCAPG has been shown to interact with DNMT3B.[4]

References

  1. ^ Jager D, Stockert E, Jager E, Gure AO, Scanlan MJ, Knuth A, Old LJ, Chen YT (Aug 2000). "Serological cloning of a melanocyte rab guanosine 5'-triphosphate-binding protein and a chromosome condensation protein from a melanoma complementary DNA library". Cancer Res 60 (13): 3584–91. PMID 10910072. 
  2. ^ Kimura K, Cuvier O, Hirano T (Feb 2001). "Chromosome condensation by a human condensin complex in Xenopus egg extracts". J Biol Chem 276 (8): 5417–20. doi:10.1074/jbc.C000873200. PMID 11136719. 
  3. ^ "Entrez Gene: NCAPG non-SMC condensin I complex, subunit G". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64151. 
  4. ^ Geiman TM, Sankpal UT, Robertson AK, Chen Y, Mazumdar M, Heale JT, Schmiesing JA, Kim W, Yokomori K, Zhao Y, Robertson KD (2004). "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery". Nucleic Acids Res. 32 (9): 2716–29. doi:10.1093/nar/gkh589. PMC 419596. PMID 15148359. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=419596. 

Further reading


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