KRT78


KRT78

Keratin 78, also known as KRT78, is a human gene.cite web | title = Entrez Gene: KRT78 keratin 78| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=196374| accessdate = ]

PBB_Summary
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summary_text = This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified.cite web | title = Entrez Gene: KRT78 keratin 78| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=196374| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Coulombe PA, Omary MB |title='Hard' and 'soft' principles defining the structure, function and regulation of keratin intermediate filaments. |journal=Curr. Opin. Cell Biol. |volume=14 |issue= 1 |pages= 110–22 |year= 2002 |pmid= 11792552 |doi=
*cite journal | author=Mischke D, Wild G |title=Polymorphic keratins in human epidermis. |journal=J. Invest. Dermatol. |volume=88 |issue= 2 |pages= 191–7 |year= 1987 |pmid= 2433356 |doi=
*cite journal | author=Rogers MA, Winter H, Langbein L, "et al." |title=Characterization of a 300 kbp region of human DNA containing the type II hair keratin gene domain. |journal=J. Invest. Dermatol. |volume=114 |issue= 3 |pages= 464–72 |year= 2000 |pmid= 10692104 |doi= 10.1046/j.1523-1747.2000.00910.x
*cite journal | author=Hesse M, Magin TM, Weber K |title=Genes for intermediate filament proteins and the draft sequence of the human genome: novel keratin genes and a surprisingly high number of pseudogenes related to keratin genes 8 and 18. |journal=J. Cell. Sci. |volume=114 |issue= Pt 14 |pages= 2569–75 |year= 2002 |pmid= 11683385 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Hesse M, Zimek A, Weber K, Magin TM |title=Comprehensive analysis of keratin gene clusters in humans and rodents. |journal=Eur. J. Cell Biol. |volume=83 |issue= 1 |pages= 19–26 |year= 2004 |pmid= 15085952 |doi=
*cite journal | author=Rogers MA, Edler L, Winter H, "et al." |title=Characterization of new members of the human type II keratin gene family and a general evaluation of the keratin gene domain on chromosome 12q13.13. |journal=J. Invest. Dermatol. |volume=124 |issue= 3 |pages= 536–44 |year= 2005 |pmid= 15737194 |doi= 10.1111/j.0022-202X.2004.23530.x
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Schweizer J, Bowden PE, Coulombe PA, "et al." |title=New consensus nomenclature for mammalian keratins. |journal=J. Cell Biol. |volume=174 |issue= 2 |pages= 169–74 |year= 2006 |pmid= 16831889 |doi= 10.1083/jcb.200603161
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134

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Look at other dictionaries:

  • Keratin — Not to be confused with kerogen, carotene, chitin, or creatine. Microscopy of keratin filaments inside cells. Keratin refers to a family of fibrous structural proteins. Keratin is the key structural material making up the outer layer of human… …   Wikipedia


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