KCNJ16

Potassium inwardly-rectifying channel, subfamily J, member 16 (KCNJ16), also known as K_IR5.1, is a human gene.cite web | title = Entrez Gene: KCNJ16 potassium inwardly-rectifying channel, subfamily J, member 16| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3773| accessdate = ]

PBB_Summary
section_title =
summary_text = Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, can form heterodimers with two other inward-rectifier type potassium channels. It may be involved in the regulation of fluid and pH balance. Three transcript variants encoding the same protein have been found for this gene.cite web | title = Entrez Gene: KCNJ16 potassium inwardly-rectifying channel, subfamily J, member 16| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3773| accessdate = ]

ee also

* Inward-rectifier potassium ion channel

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kubo Y, Adelman JP, Clapham DE, "et al." |title=International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels. |journal=Pharmacol. Rev. |volume=57 |issue= 4 |pages= 509–26 |year= 2006 |pmid= 16382105 |doi= 10.1124/pr.57.4.11
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Pearson WL, Dourado M, Schreiber M, "et al." |title=Expression of a functional Kir4 family inward rectifier K+ channel from a gene cloned from mouse liver. |journal=J. Physiol. (Lond.) |volume=514 ( Pt 3) |issue= |pages= 639–53 |year= 1999 |pmid= 9882736 |doi=
*cite journal | author=Liu Y, McKenna E, Figueroa DJ, "et al." |title=The human inward rectifier K(+) channel subunit kir5.1 (KCNJ16) maps to chromosome 17q25 and is expressed in kidney and pancreas. |journal=Cytogenet. Cell Genet. |volume=90 |issue= 1-2 |pages= 60–3 |year= 2000 |pmid= 11060447 |doi=
*cite journal | author=Derst C, Karschin C, Wischmeyer E, "et al." |title=Genetic and functional linkage of Kir5.1 and Kir2.1 channel subunits. |journal=FEBS Lett. |volume=491 |issue= 3 |pages= 305–11 |year= 2001 |pmid= 11240146 |doi=
*cite journal | author=Pessia M, Imbrici P, D'Adamo MC, "et al." |title=Differential pH sensitivity of Kir4.1 and Kir4.2 potassium channels and their modulation by heteropolymerisation with Kir5.1. |journal=J. Physiol. (Lond.) |volume=532 |issue= Pt 2 |pages= 359–67 |year= 2001 |pmid= 11306656 |doi=
*cite journal | author=Tanemoto M, Fujita A, Higashi K, Kurachi Y |title=PSD-95 mediates formation of a functional homomeric Kir5.1 channel in the brain. |journal=Neuron |volume=34 |issue= 3 |pages= 387–97 |year= 2002 |pmid= 11988170 |doi=
*cite journal | author=Konstas AA, Korbmacher C, Tucker SJ |title=Identification of domains that control the heteromeric assembly of Kir5.1/Kir4.0 potassium channels. |journal=Am. J. Physiol., Cell Physiol. |volume=284 |issue= 4 |pages= C910–7 |year= 2003 |pmid= 12456399 |doi= 10.1152/ajpcell.00479.2002
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Casamassima M, D'Adamo MC, Pessia M, Tucker SJ |title=Identification of a heteromeric interaction that influences the rectification, gating, and pH sensitivity of Kir4.1/Kir5.1 potassium channels. |journal=J. Biol. Chem. |volume=278 |issue= 44 |pages= 43533–40 |year= 2003 |pmid= 12923169 |doi= 10.1074/jbc.M306596200

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