CRYZ

Crystallin, zeta (quinone reductase), also known as CRYZ, is a human gene.cite web | title = Entrez Gene: CRYZ crystallin, zeta (quinone reductase)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1429| accessdate = ]

PBB_Summary
section_title =
summary_text = Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. One pseudogene is known to exist.cite web | title = Entrez Gene: CRYZ crystallin, zeta (quinone reductase)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1429| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Heinzmann C, Kojis TL, Gonzalez P, "et al." |title=Assignment of the zeta-crystallin gene (CRYZ) to human chromosome 1p22-p31 and identification of restriction fragment length polymorphisms. |journal=Genomics |volume=23 |issue= 2 |pages= 403–7 |year= 1995 |pmid= 7835889 |doi= 10.1006/geno.1994.1516
*cite journal | author=Gonzalez P, Rao PV, Zigler JS |title=Organization of the human zeta-crystallin/quinone reductase gene (CRYZ). |journal=Genomics |volume=21 |issue= 2 |pages= 317–24 |year= 1994 |pmid= 8088825 |doi= 10.1006/geno.1994.1272
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Gonzalez P, Rao PV, Zigler JS |title=Molecular cloning and sequencing of zeta-crystallin/quinone reductase cDNA from human liver. |journal=Biochem. Biophys. Res. Commun. |volume=191 |issue= 3 |pages= 902–7 |year= 1993 |pmid= 8466529 |doi= 10.1006/bbrc.1993.1302
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Wang W, Liu LQ, Higuchi CM, Chen H |title=Induction of NADPH:quinone reductase by dietary phytoestrogens in colonic Colo205 cells. |journal=Biochem. Pharmacol. |volume=56 |issue= 2 |pages= 189–95 |year= 1998 |pmid= 9698072 |doi=
*cite journal | author=Goenka S, Raman B, Ramakrishna T, Rao CM |title=Unfolding and refolding of a quinone oxidoreductase: alpha-crystallin, a molecular chaperone, assists its reactivation. |journal=Biochem. J. |volume=359 |issue= Pt 3 |pages= 547–56 |year= 2001 |pmid= 11672428 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Bianco NR, Perry G, Smith MA, "et al." |title=Functional implications of antiestrogen induction of quinone reductase: inhibition of estrogen-induced deoxyribonucleic acid damage. |journal=Mol. Endocrinol. |volume=17 |issue= 7 |pages= 1344–55 |year= 2004 |pmid= 12714703 |doi= 10.1210/me.2002-0382
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes