TRIM32


TRIM32

Tripartite motif-containing 32, also known as TRIM32, is a human gene.cite web | title = Entrez Gene: TRIM32 tripartite motif-containing 32| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22954| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.cite web | title = Entrez Gene: TRIM32 tripartite motif-containing 32| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22954| accessdate = ]

ee also

* tripartite motif family

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Albor A, El-Hizawi S, Horn EJ, "et al." |title=The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaB. |journal=J. Biol. Chem. |volume=281 |issue= 35 |pages= 25850–66 |year= 2006 |pmid= 16816390 |doi= 10.1074/jbc.M601655200
*cite journal | author=Lim J, Hao T, Shaw C, "et al." |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032
*cite journal | author=Chiang AP, Beck JS, Yen HJ, "et al." |title=Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11). |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 16 |pages= 6287–92 |year= 2006 |pmid= 16606853 |doi= 10.1073/pnas.0600158103
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Schoser BG, Frosk P, Engel AG, "et al." |title=Commonality of TRIM32 mutation in causing sarcotubular myopathy and LGMD2H. |journal=Ann. Neurol. |volume=57 |issue= 4 |pages= 591–5 |year= 2005 |pmid= 15786463 |doi= 10.1002/ana.20441
*cite journal | author=Benzinger A, Muster N, Koch HB, "et al." |title=Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer. |journal=Mol. Cell Proteomics |volume=4 |issue= 6 |pages= 785–95 |year= 2005 |pmid= 15778465 |doi= 10.1074/mcp.M500021-MCP200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Humphray SJ, Oliver K, Hunt AR, "et al." |title=DNA sequence and analysis of human chromosome 9. |journal=Nature |volume=429 |issue= 6990 |pages= 369–74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Frosk P, Weiler T, Nylen E, "et al." |title=Limb-girdle muscular dystrophy type 2H associated with mutation in TRIM32, a putative E3-ubiquitin-ligase gene. |journal=Am. J. Hum. Genet. |volume=70 |issue= 3 |pages= 663–72 |year= 2002 |pmid= 11822024 |doi=
*cite journal | author=Reymond A, Meroni G, Fantozzi A, "et al." |title=The tripartite motif family identifies cell compartments. |journal=EMBO J. |volume=20 |issue= 9 |pages= 2140–51 |year= 2001 |pmid= 11331580 |doi= 10.1093/emboj/20.9.2140
*cite journal | author=Weiler T, Greenberg CR, Zelinski T, "et al." |title=A gene for autosomal recessive limb-girdle muscular dystrophy in Manitoba Hutterites maps to chromosome region 9q31-q33: evidence for another limb-girdle muscular dystrophy locus. |journal=Am. J. Hum. Genet. |volume=63 |issue= 1 |pages= 140–7 |year= 1998 |pmid= 9634523 |doi=
*cite journal | author=Fridell RA, Harding LS, Bogerd HP, Cullen BR |title=Identification of a novel human zinc finger protein that specifically interacts with the activation domain of lentiviral Tat proteins. |journal=Virology |volume=209 |issue= 2 |pages= 347–57 |year= 1995 |pmid= 7778269 |doi= 10.1006/viro.1995.1266

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