CTSW (gene)


CTSW (gene)

Cathepsin W, also known as CTSW, is a human gene.cite web | title = Entrez Gene: CTSW cathepsin W| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1521| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene, a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The encoded protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells. Expression of this gene is up-regulated by interleukin-2.cite web | title = Entrez Gene: CTSW cathepsin W| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1521| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Meinhardt C, Peitz U, Treiber G, "et al." |title=Identification of a novel isoform predominantly expressed in gastric tissue and a triple-base pair polymorphism of the cathepsin W gene. |journal=Biochem. Biophys. Res. Commun. |volume=321 |issue= 4 |pages= 975–80 |year= 2004 |pmid= 15358123 |doi= 10.1016/j.bbrc.2004.07.056
*cite journal | author=Zhang Z, Henzel WJ |title=Signal peptide prediction based on analysis of experimentally verified cleavage sites. |journal=Protein Sci. |volume=13 |issue= 10 |pages= 2819–24 |year= 2005 |pmid= 15340161 |doi= 10.1110/ps.04682504
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Buhling F, Kellner U, Guenther D, "et al." |title=Characterization of novel anti-cathepsin W antibodies and cellular distribution of cathepsin W in the gastrointestinal tract. |journal=Biol. Chem. |volume=383 |issue= 7-8 |pages= 1285–9 |year= 2003 |pmid= 12437118 |doi=
*cite journal | author=Wex T, Bühling F, Wex H, "et al." |title=Human cathepsin W, a cysteine protease predominantly expressed in NK cells, is mainly localized in the endoplasmic reticulum. |journal=J. Immunol. |volume=167 |issue= 4 |pages= 2172–8 |year= 2001 |pmid= 11490002 |doi=
*cite journal | author=Wex T, Levy B, Wex H, Brömme D |title=Human cathepsins W and F form a new subgroup of cathepsins that is evolutionary separated from the cathepsin B- and L-like cysteine proteases. |journal=Adv. Exp. Med. Biol. |volume=477 |issue= |pages= 271–80 |year= 2000 |pmid= 10849754 |doi=
*cite journal | author=Brinkworth RI, Tort JF, Brindley PJ, Dalton JP |title=Phylogenetic relationships and theoretical model of human cathepsin W (lymphopain), a cysteine proteinase from cytotoxic T lymphocytes. |journal=Int. J. Biochem. Cell Biol. |volume=32 |issue= 3 |pages= 373–84 |year= 2000 |pmid= 10716634 |doi=
*cite journal | author=Wex T, Levy B, Wex H, Brömme D |title=Human cathepsins F and W: A new subgroup of cathepsins. |journal=Biochem. Biophys. Res. Commun. |volume=259 |issue= 2 |pages= 401–7 |year= 1999 |pmid= 10362521 |doi= 10.1006/bbrc.1999.0700
*cite journal | author=Brown J, Matutes E, Singleton A, "et al." |title=Lymphopain, a cytotoxic T and natural killer cell-associated cysteine proteinase. |journal=Leukemia |volume=12 |issue= 11 |pages= 1771–81 |year= 1998 |pmid= 9823953 |doi=
*cite journal | author=Wex T, Levy B, Smeekens SP, "et al." |title=Genomic structure, chromosomal localization, and expression of human cathepsin W. |journal=Biochem. Biophys. Res. Commun. |volume=248 |issue= 2 |pages= 255–61 |year= 1998 |pmid= 9675123 |doi= 10.1006/bbrc.1998.8954
*cite journal | author=Linnevers C, Smeekens SP, Brömme D |title=Human cathepsin W, a putative cysteine protease predominantly expressed in CD8+ T-lymphocytes. |journal=FEBS Lett. |volume=405 |issue= 3 |pages= 253–9 |year= 1997 |pmid= 9108299 |doi=

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