- Cytidine monophosphate
Cytidine monophosphate Identifiers CAS number PubChem ChemSpider ChEBI ChEMBL Jmol-3D images Image 1 Properties Molecular formula C9H14N3O8P Molar mass 323.20 g/mol Acidity (pKa) 0.8, 4.5, 6.3 (what is: /?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Cytidine monophosphate, also known as 5'-cytidylic acid or simply cytidylate, and abbreviated CMP, is a nucleotide that is used as a monomer in RNA. It is an ester of phosphoric acid with the nucleoside cytidine. CMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase cytosine; hence, a ribonucleoside monophosphate. As a substituent it takes the form of the prefix cytidylyl-.
CMP can be phosphorylated to Cytidine diphosphate by the enzyme CMP kinase, with Adenosine triphosphate or guanine triphosphate donating the phosphate group. Since Cytidine triphosphate is generated by amination of uridine triphosphate, the main source of CMP is from RNA being decomposed, eg. by RNAse.
CMP is used to activate mannose in metabolism.
- ^ Pascal JM (February 2008). "DNA and RNA ligases: structural variations and shared mechanisms". Curr. Opin. Struct. Biol. 18 (1): 96–105. doi:10.1016/j.sbi.2007.12.008. PMID 18262407. http://linkinghub.elsevier.com/retrieve/pii/S0959-440X(07)00208-4.
Nucleic acid constituents Nucleobase Nucleoside Nucleotide
Nucleoside diphosphate Nucleoside triphosphate biochemical families: prot · nucl · carb (glpr, alco, glys) · lipd (fata/i, phld, strd, gllp, eico) · amac/i · ncbs/i · ttpy/i
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