ARL6


ARL6

ADP-ribosylation factor-like 6, also known as ARL6, is a human gene.cite web | title = Entrez Gene: ARL6 ADP-ribosylation factor-like 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84100| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene belongs to the ARF family of GTP-binding proteins. ARF proteins are important regulators of cellular traffic and are the founding members of an expanding family of homologous proteins and genomic sequences. They depart from other small GTP-binding proteins by a unique structural device that implements front-back communication from the N-terminus to the nucleotide-binding site. Studies of the mouse ortholog of this protein suggest an involvement in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been described.cite web | title = Entrez Gene: ARL6 ADP-ribosylation factor-like 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84100| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Sheffield VC, Carmi R, Kwitek-Black A, "et al." |title=Identification of a Bardet-Biedl syndrome locus on chromosome 3 and evaluation of an efficient approach to homozygosity mapping. |journal=Hum. Mol. Genet. |volume=3 |issue= 8 |pages= 1331–5 |year= 1995 |pmid= 7987310 |doi=
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Jacobs S, Schilf C, Fliegert F, "et al." |title=ADP-ribosylation factor (ARF)-like 4, 6, and 7 represent a subgroup of the ARF family characterization by rapid nucleotide exchange and a nuclear localization signal. |journal=FEBS Lett. |volume=456 |issue= 3 |pages= 384–8 |year= 1999 |pmid= 10462049 |doi=
*cite journal | author=Ingley E, Williams JH, Walker CE, "et al." |title=A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit. |journal=FEBS Lett. |volume=459 |issue= 1 |pages= 69–74 |year= 1999 |pmid= 10508919 |doi=
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Wiemann S, Weil B, Wellenreuther R, "et al." |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701
*cite journal | author=Pasqualato S, Renault L, Cherfils J |title=Arf, Arl, Arp and Sar proteins: a family of GTP-binding proteins with a structural device for 'front-back' communication. |journal=EMBO Rep. |volume=3 |issue= 11 |pages= 1035–41 |year= 2003 |pmid= 12429613 |doi= 10.1093/embo-reports/kvf221
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Chiang AP, Nishimura D, Searby C, "et al." |title=Comparative genomic analysis identifies an ADP-ribosylation factor-like gene as the cause of Bardet-Biedl syndrome (BBS3). |journal=Am. J. Hum. Genet. |volume=75 |issue= 3 |pages= 475–84 |year= 2004 |pmid= 15258860 |doi= 10.1086/423903
*cite journal | author=Fan Y, Esmail MA, Ansley SJ, "et al." |title=Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome. |journal=Nat. Genet. |volume=36 |issue= 9 |pages= 989–93 |year= 2004 |pmid= 15314642 |doi= 10.1038/ng1414
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Wiemann S, Arlt D, Huber W, "et al." |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Mehrle A, Rosenfelder H, Schupp I, "et al." |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139

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