G-2 and S-phase expressed 1, also known as GTSE1, is a human gene.cite web | title = Entrez Gene: GTSE1 G-2 and S-phase expressed 1| url =| accessdate = ]

section_title =
summary_text = The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.cite web | title = Entrez Gene: GTSE1 G-2 and S-phase expressed 1| url =| accessdate = ]


Further reading

citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Dunham I, Shimizu N, Roe BA, "et al." |title=The DNA sequence of human chromosome 22. |journal=Nature |volume=402 |issue= 6761 |pages= 489–95 |year= 1999 |pmid= 10591208 |doi= 10.1038/990031
*cite journal | author=Monte M, Collavin L, Lazarevic D, "et al." |title=Cloning, chromosome mapping and functional characterization of a human homologue of murine gtse-1 (B99) gene. |journal=Gene |volume=254 |issue= 1-2 |pages= 229–36 |year= 2000 |pmid= 10974554 |doi=
*cite journal | author=Collavin L, Monte M, Verardo R, "et al." |title=Cell-cycle regulation of the p53-inducible gene B99. |journal=FEBS Lett. |volume=481 |issue= 1 |pages= 57–62 |year= 2000 |pmid= 10984615 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Monte M, Benetti R, Buscemi G, "et al." |title=The cell cycle-regulated protein human GTSE-1 controls DNA damage-induced apoptosis by affecting p53 function. |journal=J. Biol. Chem. |volume=278 |issue= 32 |pages= 30356–64 |year= 2003 |pmid= 12750368 |doi= 10.1074/jbc.M302902200
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Monte M, Benetti R, Collavin L, "et al." |title=hGTSE-1 expression stimulates cytoplasmic localization of p53. |journal=J. Biol. Chem. |volume=279 |issue= 12 |pages= 11744–52 |year= 2004 |pmid= 14707141 |doi= 10.1074/jbc.M311123200
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Cheng J, Kapranov P, Drenkow J, "et al." |title=Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution. |journal=Science |volume=308 |issue= 5725 |pages= 1149–54 |year= 2005 |pmid= 15790807 |doi= 10.1126/science.1108625
*cite journal | author=Kapranov P, Drenkow J, Cheng J, "et al." |title=Examples of the complex architecture of the human transcriptome revealed by RACE and high-density tiling arrays. |journal=Genome Res. |volume=15 |issue= 7 |pages= 987–97 |year= 2005 |pmid= 15998911 |doi= 10.1101/gr.3455305
*cite journal | author=Beausoleil SA, Villén J, Gerber SA, "et al." |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240

update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes

Wikimedia Foundation. 2010.

См. также в других словарях:

  • B99 — may refer to : * Bundesstraße 99, a German road * Katschberg Straße, an Austrian road * Sicilian Defence, Najdorf Variation, according to the list of chess openings * Lola B99/50, a race car * Beechcraft Model 99, an airplane * an alternative… …   Wikipedia

Поделиться ссылкой на выделенное

Прямая ссылка:
Нажмите правой клавишей мыши и выберите «Копировать ссылку»