Aquaporin 5, also known as AQP5, is a human gene.cite web | title = Entrez Gene: AQP5 aquaporin 5| url =| accessdate = ]

section_title =
summary_text = Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13.cite web | title = Entrez Gene: AQP5 aquaporin 5| url =| accessdate = ]

ee also

* Aquaporin


Further reading

citations =
*cite journal | author=Verkman AS |title=Role of aquaporin water channels in eye function. |journal=Exp. Eye Res. |volume=76 |issue= 2 |pages= 137–43 |year= 2003 |pmid= 12565800 |doi=
*cite journal | author=Lee MD, Bhakta KY, Raina S, "et al." |title=The human Aquaporin-5 gene. Molecular characterization and chromosomal localization. |journal=J. Biol. Chem. |volume=271 |issue= 15 |pages= 8599–604 |year= 1996 |pmid= 8621489 |doi=
*cite journal | author=Ma T, Yang B, Umenishi F, Verkman AS |title=Closely spaced tandem arrangement of AQP2, AQP5, and AQP6 genes in a 27-kilobase segment at chromosome locus 12q13. |journal=Genomics |volume=43 |issue= 3 |pages= 387–9 |year= 1997 |pmid= 9268644 |doi= 10.1006/geno.1997.4836
*cite journal | author=Smith JK, Siddiqui AA, Modica LA, "et al." |title=Interferon-alpha upregulates gene expression of aquaporin-5 in human parotid glands. |journal=J. Interferon Cytokine Res. |volume=19 |issue= 8 |pages= 929–35 |year= 1999 |pmid= 10476940 |doi= 10.1089/107999099313479
*cite journal | author=Kreda SM, Gynn MC, Fenstermacher DA, "et al." |title=Expression and localization of epithelial aquaporins in the adult human lung. |journal=Am. J. Respir. Cell Mol. Biol. |volume=24 |issue= 3 |pages= 224–34 |year= 2001 |pmid= 11245621 |doi=
*cite journal | author=Gresz V, Kwon TH, Hurley PT, "et al." |title=Identification and localization of aquaporin water channels in human salivary glands. |journal=Am. J. Physiol. Gastrointest. Liver Physiol. |volume=281 |issue= 1 |pages= G247–54 |year= 2001 |pmid= 11408278 |doi=
*cite journal | author=Nejsum LN, Kwon TH, Jensen UB, "et al." |title=Functional requirement of aquaporin-5 in plasma membranes of sweat glands. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 1 |pages= 511–6 |year= 2002 |pmid= 11773623 |doi= 10.1073/pnas.012588099
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Burghardt B, Elkaer ML, Kwon TH, "et al." |title=Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas. |journal=Gut |volume=52 |issue= 7 |pages= 1008–16 |year= 2003 |pmid= 12801959 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Chen Z, Wang X, Gao L, "et al." |title=Regulation of MUC5AC mucin secretion by depletion of AQP5 in SPC-A1 cells. |journal=Biochem. Biophys. Res. Commun. |volume=342 |issue= 3 |pages= 775–81 |year= 2006 |pmid= 16500622 |doi= 10.1016/j.bbrc.2006.01.103
*cite journal | author=Sidhaye VK, Güler AD, Schweitzer KS, "et al." |title=Transient receptor potential vanilloid 4 regulates aquaporin-5 abundance under hypotonic conditions. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 12 |pages= 4747–52 |year= 2006 |pmid= 16537379 |doi= 10.1073/pnas.0511211103
*cite journal | author=Pedersen PS, Braunstein TH, Jørgensen A, "et al." |title=Stimulation of aquaporin-5 and transepithelial water permeability in human airway epithelium by hyperosmotic stress. |journal=Pflugers Arch. |volume=453 |issue= 6 |pages= 777–85 |year= 2007 |pmid= 17043812 |doi= 10.1007/s00424-006-0157-3
*cite journal | author=Skowron-zwarg M, Boland S, Caruso N, "et al." |title=Interleukin-13 interferes with CFTR and AQP5 expression and localization during human airway epithelial cell differentiation. |journal=Exp. Cell Res. |volume=313 |issue= 12 |pages= 2695–702 |year= 2007 |pmid= 17553491 |doi= 10.1016/j.yexcr.2007.02.035

External links


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