GOT1

Glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1), also known as GOT1, is a human gene.cite web | title = Entrez Gene: GOT1 glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2805| accessdate = ]

PBB_Summary
section_title =
summary_text = Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.cite web | title = Entrez Gene: GOT1 glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2805| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Panteghini M |title=Aspartate aminotransferase isoenzymes. |journal=Clin. Biochem. |volume=23 |issue= 4 |pages= 311–9 |year= 1990 |pmid= 2225456 |doi=
*cite journal | author=Doonan S, Barra D, Bossa F |title=Structural and genetic relationships between cytosolic and mitochondrial isoenzymes. |journal=Int. J. Biochem. |volume=16 |issue= 12 |pages= 1193–9 |year= 1985 |pmid= 6397370 |doi=
*cite journal | author=Kamei S, Ohkubo A, Yamanaka M |title=Apoenzyme of aspartate aminotransferase isozymes in serum and its diagnostic usefullness for hepatic diseases. |journal=Clin. Chim. Acta |volume=96 |issue= 1-2 |pages= 97–105 |year= 1979 |pmid= 225064 |doi=
*cite journal | author=Bousquet-Lemercier B, Pol S, Pavé-Preux M, "et al." |title=Properties of human liver cytosolic aspartate aminotransferase mRNAs generated by alternative polyadenylation site selection. |journal=Biochemistry |volume=29 |issue= 22 |pages= 5293–9 |year= 1990 |pmid= 1974457 |doi=
*cite journal | author=Doyle JM, Schininà ME, Bossa F, Doonan S |title=The amino acid sequence of cytosolic aspartate aminotransferase from human liver. |journal=Biochem. J. |volume=270 |issue= 3 |pages= 651–7 |year= 1990 |pmid= 2241899 |doi=
*cite journal | author=Pol S, Bousquet-Lemercier B, Pavé-Preux M, "et al." |title=Chromosomal localization of human aspartate aminotransferase genes by in situ hybridization. |journal=Hum. Genet. |volume=83 |issue= 2 |pages= 159–64 |year= 1989 |pmid= 2777255 |doi=
*cite journal | author=Pol S, Bousquet-Lemercier B, Pave-Preux M, "et al." |title=Nucleotide sequence and tissue distribution of the human mitochondrial aspartate aminotransferase mRNA. |journal=Biochem. Biophys. Res. Commun. |volume=157 |issue= 3 |pages= 1309–15 |year= 1989 |pmid= 3207426 |doi=
*cite journal | author=Andersson B, Wentland MA, Ricafrente JY, "et al." |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138
*cite journal | author=Yu W, Andersson B, Worley KC, "et al." |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=
*cite journal | author=Wang CY, Huang YQ, Shi JD, "et al." |title=Genetic homogeneity, high-resolution mapping, and mutation analysis of the urofacial (Ochoa) syndrome and exclusion of the glutamate oxaloacetate transaminase gene (GOT1) in the critical region as the disease gene. |journal=Am. J. Med. Genet. |volume=84 |issue= 5 |pages= 454–9 |year= 1999 |pmid= 10360399 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Miyake Y, Eguchi H, Shinchi K, "et al." |title=Glucose intolerance and serum aminotransferase activities in Japanese men. |journal=J. Hepatol. |volume=38 |issue= 1 |pages= 18–23 |year= 2003 |pmid= 12480555 |doi=
*cite journal | author=Deloukas P, Earthrowl ME, Grafham DV, "et al." |title=The DNA sequence and comparative analysis of human chromosome 10. |journal=Nature |volume=429 |issue= 6990 |pages= 375–81 |year= 2004 |pmid= 15164054 |doi= 10.1038/nature02462
*cite journal | author=Wu KL, Lu SN, Changchien CS, "et al." |title=Sequential changes of serum aminotransferase levels in patients with severe acute respiratory syndrome. |journal=Am. J. Trop. Med. Hyg. |volume=71 |issue= 2 |pages= 125–8 |year= 2004 |pmid= 15306699 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Totan A, Greabu M, Totan C, Spinu T |title=Salivary aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase: possible markers in periodontal diseases? |journal=Clin. Chem. Lab. Med. |volume=44 |issue= 5 |pages= 612–5 |year= 2006 |pmid= 16681433 |doi= 10.1515/CCLM.2006.096
*cite journal | author=Dubern B, Girardet JP, Tounian P |title=Insulin resistance and ferritin as major determinants of abnormal serum aminotransferase in severely obese children. |journal=International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity |volume=1 |issue= 2 |pages= 77–82 |year= 2007 |pmid= 17907318 |doi=

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