CD6

CD6

CD6 (Cluster of Differentiation 6) is a human protein encoded by the gene|CD6 gene.cite web | title = Entrez Gene: CD6 CD6 molecule| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=923| accessdate = ]

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ee also

* Cluster of differentiation

References

Further reading

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*cite journal | author=Aruffo A, Melnick MB, Linsley PS, Seed B |title=The lymphocyte glycoprotein CD6 contains a repeated domain structure characteristic of a new family of cell surface and secreted proteins. |journal=J. Exp. Med. |volume=174 |issue= 4 |pages= 949–52 |year= 1991 |pmid= 1919444 |doi=
*cite journal | author=Swack JA, Mier JW, Romain PL, "et al." |title=Biosynthesis and post-translational modification of CD6, a T cell signal-transducing molecule. |journal=J. Biol. Chem. |volume=266 |issue= 11 |pages= 7137–43 |year= 1991 |pmid= 2016320 |doi=
*cite journal | author=Tsuge I, Utsumi KR, Ueda R, "et al." |title=Assignment of gene coding human T-cell differentiation antigen, Tp120, to chromosome 11. |journal=Somat. Cell Mol. Genet. |volume=11 |issue= 3 |pages= 217–22 |year= 1985 |pmid= 3923629 |doi=
*cite journal | author=Whitney GS, Starling GC, Bowen MA, "et al." |title=The membrane-proximal scavenger receptor cysteine-rich domain of CD6 contains the activated leukocyte cell adhesion molecule binding site. |journal=J. Biol. Chem. |volume=270 |issue= 31 |pages= 18187–90 |year= 1995 |pmid= 7543097 |doi=
*cite journal | author=Robinson WH, Neuman de Vegvar HE, Prohaska SS, "et al." |title=Human CD6 possesses a large, alternatively spliced cytoplasmic domain. |journal=Eur. J. Immunol. |volume=25 |issue= 10 |pages= 2765–9 |year= 1995 |pmid= 7589069 |doi=
*cite journal | author=Wee S, Schieven GL, Kirihara JM, "et al." |title=Tyrosine phosphorylation of CD6 by stimulation of CD3: augmentation by the CD4 and CD2 coreceptors. |journal=J. Exp. Med. |volume=177 |issue= 1 |pages= 219–23 |year= 1993 |pmid= 7678115 |doi=
*cite journal | author=Bowen MA, Whitney GS, Neubauer M, "et al." |title=Structure and chromosomal location of the human CD6 gene: detection of five human CD6 isoforms. |journal=J. Immunol. |volume=158 |issue= 3 |pages= 1149–56 |year= 1997 |pmid= 9013954 |doi=
*cite journal | author=Kobarg J, Whitney GS, Palmer D, "et al." |title=Analysis of the tyrosine phosphorylation and calcium fluxing of human CD6 isoforms with different cytoplasmatic domains. |journal=Eur. J. Immunol. |volume=27 |issue= 11 |pages= 2971–80 |year= 1998 |pmid= 9394826 |doi=
*cite journal | author=Singer NG, Mitra R, Lialios F, "et al." |title=CD6 dependent interactions of T cells and keratinocytes: functional evidence for a second CD6 ligand on gamma-interferon activated keratinocytes. |journal=Immunol. Lett. |volume=58 |issue= 1 |pages= 9–14 |year= 1998 |pmid= 9436462 |doi=
*cite journal | author=Gimferrer I, Farnós M, Calvo M, "et al." |title=The accessory molecules CD5 and CD6 associate on the membrane of lymphoid T cells. |journal=J. Biol. Chem. |volume=278 |issue= 10 |pages= 8564–71 |year= 2003 |pmid= 12473675 |doi= 10.1074/jbc.M209591200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Shin BK, Wang H, Yim AM, "et al." |title=Global profiling of the cell surface proteome of cancer cells uncovers an abundance of proteins with chaperone function. |journal=J. Biol. Chem. |volume=278 |issue= 9 |pages= 7607–16 |year= 2003 |pmid= 12493773 |doi= 10.1074/jbc.M210455200
*cite journal | author=Gimferrer I, Ibáñez A, Farnós M, "et al." |title=The lymphocyte receptor CD6 interacts with syntenin-1, a scaffolding protein containing PDZ domains. |journal=J. Immunol. |volume=175 |issue= 3 |pages= 1406–14 |year= 2005 |pmid= 16034076 |doi=
*cite journal | author=Kato Y, Tanaka Y, Hayashi M, "et al." |title=Involvement of CD166 in the activation of human gamma delta T cells by tumor cells sensitized with nonpeptide antigens. |journal=J. Immunol. |volume=177 |issue= 2 |pages= 877–84 |year= 2006 |pmid= 16818742 |doi=
*cite journal | author=Ibáñez A, Sarrias MR, Farnós M, "et al." |title=Mitogen-activated protein kinase pathway activation by the CD6 lymphocyte surface receptor. |journal=J. Immunol. |volume=177 |issue= 2 |pages= 1152–9 |year= 2006 |pmid= 16818773 |doi=
*cite journal | author=Hassan NJ, Simmonds SJ, Clarkson NG, "et al." |title=CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76. |journal=Mol. Cell. Biol. |volume=26 |issue= 17 |pages= 6727–38 |year= 2006 |pmid= 16914752 |doi= 10.1128/MCB.00688-06
*cite journal | author=Castro MA, Oliveira MI, Nunes RJ, "et al." |title=Extracellular isoforms of CD6 generated by alternative splicing regulate targeting of CD6 to the immunological synapse. |journal=J. Immunol. |volume=178 |issue= 7 |pages= 4351–61 |year= 2007 |pmid= 17371992 |doi=
*cite journal | author=Sarrias MR, Farnós M, Mota R, "et al." |title=CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=104 |issue= 28 |pages= 11724–9 |year= 2007 |pmid= 17601777 |doi= 10.1073/pnas.0702815104

External links

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