Transcription elongation factor A (SII), 2, also known as TCEA2, is a human gene.cite web | title = Entrez Gene: TCEA2 transcription elongation factor A (SII), 2| url =| accessdate = ]

section_title =
summary_text = The protein encoded by this gene is found in the nucleus, where it functions as an SII class transcription elongation factor. Elongation factors in this class are responsible for releasing RNA polymerase II ternary complexes from transcriptional arrest at template-encoded arresting sites. The encoded protein has been shown to interact with general transcription factor IIB, a basal transcription factor. Two transcript variants encoding different isoforms have been found for this gene.cite web | title = Entrez Gene: TCEA2 transcription elongation factor A (SII), 2| url =| accessdate = ]


Further reading

citations =
*cite journal | author=Kato H, Sumimoto H, Pognonec P, "et al." |title=HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factors. |journal=Genes Dev. |volume=6 |issue= 4 |pages= 655–66 |year= 1992 |pmid= 1559613 |doi=
*cite journal | author=Umehara T, Kida S, Yamamoto T, Horikoshi M |title=Isolation and characterization of a cDNA encoding a new type of human transcription elongation factor S-II. |journal=Gene |volume=167 |issue= 1-2 |pages= 297–302 |year= 1996 |pmid= 8566795 |doi=
*cite journal | author=Weaver ZA, Kane CM |title=Genomic characterization of a testis-specific TFIIS (TCEA2) gene. |journal=Genomics |volume=46 |issue= 3 |pages= 516–9 |year= 1998 |pmid= 9441762 |doi= 10.1006/geno.1997.5073
*cite journal | author=Li XY, Green MR |title=The HIV-1 Tat cellular coactivator Tat-SF1 is a general transcription elongation factor. |journal=Genes Dev. |volume=12 |issue= 19 |pages= 2992–6 |year= 1998 |pmid= 9765201 |doi=
*cite journal | author=Trembley JH, Hu D, Hsu LC, "et al." |title=PITSLRE p110 protein kinases associate with transcription complexes and affect their activity. |journal=J. Biol. Chem. |volume=277 |issue= 4 |pages= 2589–96 |year= 2002 |pmid= 11709559 |doi= 10.1074/jbc.M109755200
*cite journal | author=Deloukas P, Matthews LH, Ashurst J, "et al." |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a
*cite journal | author=Sijbrandi R, Fiedler U, Timmers HT |title=RNA polymerase II complexes in the very early phase of transcription are not susceptible to TFIIS-induced exonucleolytic cleavage. |journal=Nucleic Acids Res. |volume=30 |issue= 11 |pages= 2290–8 |year= 2002 |pmid= 12034815 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Saso K, Ito T, Natori S, Sekimizu K |title=Identification of a novel tissue-specific transcriptional activator FESTA as a protein that interacts with the transcription elongation factor S-II. |journal=J. Biochem. |volume=133 |issue= 4 |pages= 493–500 |year= 2004 |pmid= 12761297 |doi=
*cite journal | author=Tamura K, Miyata K, Sugahara K, "et al." |title=Identification of EloA-BP1, a novel Elongin A binding protein with an exonuclease homology domain. |journal=Biochem. Biophys. Res. Commun. |volume=309 |issue= 1 |pages= 189–95 |year= 2003 |pmid= 12943681 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Nakata A, Ito T, Nagata M, "et al." |title=GRIP1tau, a novel PDZ domain-containing transcriptional activator, cooperates with the testis-specific transcription elongation factor SII-T1. |journal=Genes Cells |volume=9 |issue= 11 |pages= 1125–35 |year= 2005 |pmid= 15507123 |doi= 10.1111/j.1365-2443.2004.00795.x
*cite journal | author=Stelzl U, Worm U, Lalowski M, "et al." |title=A human protein-protein interaction network: a resource for annotating the proteome. |journal=Cell |volume=122 |issue= 6 |pages= 957–68 |year= 2005 |pmid= 16169070 |doi= 10.1016/j.cell.2005.08.029
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Palangat M, Renner DB, Price DH, Landick R |title=A negative elongation factor for human RNA polymerase II inhibits the anti-arrest transcript-cleavage factor TFIIS. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 42 |pages= 15036–41 |year= 2005 |pmid= 16214896 |doi= 10.1073/pnas.0409405102
*cite journal | author=Kuraoka I, Suzuki K, Ito S, "et al." |title=RNA polymerase II bypasses 8-oxoguanine in the presence of transcription elongation factor TFIIS. |journal=DNA Repair (Amst.) |volume=6 |issue= 6 |pages= 841–51 |year= 2007 |pmid= 17374514 |doi= 10.1016/j.dnarep.2007.01.014

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