- ATP5J
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6, also known as ATP5J, is a human
gene .cite web | title = Entrez Gene: ATP5J ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=522| accessdate = ]PBB_Summary
section_title =
summary_text = Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, F0, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The F0 seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the F6 subunit of the F0 complex, required for F1 and F0 interactions. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.cite web | title = Entrez Gene: ATP5J ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=522| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Kinosita K, Yasuda R, Noji H |title=F1-ATPase: a highly efficient rotary ATP machine. |journal=Essays Biochem. |volume=35 |issue= |pages= 3–18 |year= 2003 |pmid= 12471886 |doi=
*cite journal | author=Oster G, Wang H |title=Rotary protein motors. |journal=Trends Cell Biol. |volume=13 |issue= 3 |pages= 114–21 |year= 2003 |pmid= 12628343 |doi=
*cite journal | author=Leyva JA, Bianchet MA, Amzel LM |title=Understanding ATP synthesis: structure and mechanism of the F1-ATPase (Review). |journal=Mol. Membr. Biol. |volume=20 |issue= 1 |pages= 27–33 |year= 2003 |pmid= 12745923 |doi=
*cite journal | author=Hochstrasser DF, Frutiger S, Paquet N, "et al." |title=Human liver proteinjournal=Electrophoresis |volume=13 |issue= 12 |pages= 992–1001 |year= 1993 |pmid= 1286669 |doi=
*cite journal | author=Javed AA, Ogata K, Sanadi DR |title=Human mitochondrial ATP synthase: cloning cDNA for the nuclear-encoded precursor of coupling factor 6. |journal=Gene |volume=97 |issue= 2 |pages= 307–10 |year= 1991 |pmid= 1825642 |doi=
*cite journal | author=Higuti T, Tsurumi C, Kawamura Y, "et al." |title=Molecular cloning of cDNA for the import precursor of human coupling factor 6 of H(+)-ATP synthase in mitochondria. |journal=Biochem. Biophys. Res. Commun. |volume=178 |issue= 2 |pages= 793–9 |year= 1991 |pmid= 1830479 |doi=
*cite journal | author=Yan WL, Lerner TJ, Haines JL, Gusella JF |title=Sequence analysis and mapping of a novel human mitochondrial ATP synthase subunit 9 cDNA (ATP5G3). |journal=Genomics |volume=24 |issue= 2 |pages= 375–7 |year= 1995 |pmid= 7698763 |doi= 10.1006/geno.1994.1631
*cite journal | author=Elston T, Wang H, Oster G |title=Energy transduction in ATP synthase. |journal=Nature |volume=391 |issue= 6666 |pages= 510–3 |year= 1998 |pmid= 9461222 |doi= 10.1038/35185
*cite journal | author=Webster KA, Oliver NA, Wallace DC |title=Assignment of an oligomycin-resistance locus to human chromosome 10. |journal=Somatic Cell Genet. |volume=8 |issue= 2 |pages= 223–44 |year= 1998 |pmid= 9732751 |doi=
*cite journal | author=Wang H, Oster G |title=Energy transduction in the F1 motor of ATP synthase. |journal=Nature |volume=396 |issue= 6708 |pages= 279–82 |year= 1998 |pmid= 9834036 |doi= 10.1038/24409
*cite journal | author=Hattori M, Fujiyama A, Taylor TD, "et al." |title=The DNA sequence of human chromosome 21. |journal=Nature |volume=405 |issue= 6784 |pages= 311–9 |year= 2000 |pmid= 10830953 |doi= 10.1038/35012518
*cite journal | author=Wiemann S, Weil B, Wellenreuther R, "et al." |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Osanai T, Nakamura M, Sasaki S, "et al." |title=Plasma concentration of coupling factor 6 and cardiovascular events in patients with end-stage renal disease. |journal=Kidney Int. |volume=64 |issue= 6 |pages= 2291–7 |year= 2004 |pmid= 14633154 |doi= 10.1046/j.1523-1755.2003.00334.x
*cite journal | author=Cross RL |title=Molecular motors: turning the ATP motor. |journal=Nature |volume=427 |issue= 6973 |pages= 407–8 |year= 2004 |pmid= 14749816 |doi= 10.1038/427407b
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Jacobs LJ, de Coo IF, Nijland JG, "et al." |title=Transmission and prenatal diagnosis of the T9176C mitochondrial DNA mutation. |journal=Mol. Hum. Reprod. |volume=11 |issue= 3 |pages= 223–8 |year= 2005 |pmid= 15709156 |doi= 10.1093/molehr/gah152PBB_Controls
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